Results 51 to 60 of about 2,400 (204)

Comment on 'Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets' by Lam et al. [PDF]

open access: yes, 2017
Lam et al. (2017) reported a large-scale genome-wide association study (GWAS) of cognitive ability. They used the new analytical method of Multi-Trait Analysis of GWAS (MTAG) (Turley et al., 2017) to combine GWAS data sets on the correlated phenotypes of
Lam, W. D. Hill
core   +3 more sources

A Novel Functional Ingredient Derived From a Mixture of Mulberry (Morus alba L.) Leaves and Butterfly Pea (Clitoria ternatea L.) Flowers Enhances Rapid Eye Movement Sleep, Cognitive Function, and Anxiolytic Behavior via GABAA Receptor‐Dependent Mechanism in Rats

open access: yesOxidative Medicine and Cellular Longevity, Volume 2026, Issue 1, 2026.
The neuropharmacological benefits for sleep quality and mental health from the extracts of Morus alba L. leaves (MA) and Clitoria ternatea L. flowers (CT) have been revealed previously. However, due to synergistic interactions of polyherbal ingredients, the positive effects of MA mixed with CT are still controversial. Preliminary outcomes from in vitro
Jakkrit Nukitram   +11 more
wiley   +1 more source

DETERMINATION OF 3-HYDROXY-3-PYRROLINE-2-ONE IN URINE AND STUDY OF ITS EXCRETION FROM THE ORGANISM OF LABORATORY ANIMALS

open access: yesФармация и фармакология (Пятигорск), 2017
It is known that almost any disease of the central nervous system is accompanied by the development of cognitive disorders. The drugs of choice in the complex therapy in this case are nootropics. On the world market racetam group, i.e.
E. A. Bulgakova   +2 more
doaj   +1 more source

Beware the cult of 'tech fixing' -- it's why America is eyeing the nuclear button [PDF]

open access: yes, 2017
On technological fixes and the dangers of the shallow short-term problem solving of social, political and economic problems by technological means ...
Johnston, Sean F.
core  

Advances in Pharmacological Insights of Borago officinalis: A Comprehensive Review

open access: yesBiological Diversity, Volume 2, Issue 4, Page 193-205, December 2025.
ABSTRACT Recent growth in phytotherapy and product‐based drug development has increased interest in this plant because of its broad pharmacological activity. This review aims to examine the pharmacological activities, mechanisms, and potential applications of Borago officinalis, focusing on its primary bioactive constituents and therapeutic ...
Zahra Sufwan   +2 more
wiley   +1 more source

Structure‐Guided Identification and Evaluation of Epalrestat and Ranirestat‐Like Compounds Against Aldose Reductase: Therapeutic Management of Diabetic Neuropathy

open access: yesChemistryOpen, Volume 14, Issue 12, December 2025.
Structure‐based virtual screening of PubChem compounds identifies two novel epalrestat and ranirestat‐like inhibitors with improved affinity and pharmacokinetic profiles targeting aldose reductase. Molecular docking, ADMET filtering, and 500‐ns molecular dynamics simulations confirm the stability and interaction specificity of the candidates ...
Mohd Shahnawaz Khan   +3 more
wiley   +1 more source

Clinical pharmacology of modern nootropics and their role in the therapy of kinesia (sickness)

open access: yesМедицинский совет, 2013
Present-day globalization of the world economy, stronger communication in business, science, education and leisure, growth of the population migration (including seasonal) have led to an increase in the incidence of kinesia (sickness).
V. V. Kosarev, S. A. Babanov
doaj   +1 more source

The efficacy and safety of animal-derived nootropics in cognitive disorders: Systematic review and meta-analysis

open access: yesCerebral Circulation - Cognition and Behavior, 2021
Background: The animal-derived nootropics, Cerebrolysin, Actovegin and Cortexin, may have potential in treating neurocognitive disorders. Although these drugs have international usage, reports on their efficacy have been conflicting.
Rayan A. Alsulaimani, Terence J. Quinn
doaj   +1 more source

The pharmacist’s response to the needs of patients undergoing treatment with psychotropic medication [PDF]

open access: yes, 1999
The usage of psychotropic (Table 1) medication is considerable world wide. In Malta, this can be attested to by the numerous studies that have been conducted by the University of Malta Department of Pharmacy (in conjuction with other institutions and ...
Sant Fournier, Mary Ann
core  

Therapeutic strategies in vascular cognitive impairment: A systematic review and meta‐analysis

open access: yesAlzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION Vascular cognitive impairment (VCI) is a common, heterogeneous condition, currently lacking approved treatments. METHODS We reviewed therapeutic strategies tested in VCI and meta‐analyzed efficacy data for eligible interventions to assess whether previously tested treatments warranted reconsideration.
Federico Masserini   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy