Activation of NK1receptors in the locus coeruleus induces analgesia through noradrenergic‐mediated descending inhibition in a rat model of neuropathic pain [PDF]
Yumi Muto +3 more
openalex +1 more source
Activation of locus coeruleus-spinal cord noradrenergic neurons alleviates neuropathic pain in mice via reducing neuroinflammation from astrocytes and microglia in spinal dorsal horn [PDF]
Juan Li +10 more
openalex +1 more source
Distinct Roles of Dopamine and Noradrenaline in Physical Fatigue
ABSTRACT This triple‐blinded randomized crossover study investigated the roles of dopamine (DA) and noradrenaline (NA) in regulating exercise performance and fatigue using acute pharmacological manipulation. Eighteen healthy adults (9 males and 9 females; mean age = 23.4 ± 2.2 years) completed three experimental conditions.
Y. Laurisa Arenales Arauz +8 more
wiley +1 more source
Morphological alterations related to depressive symptoms in mild cognitive impairment were primarily involved in emotion and affective processing, showing strong correspondence with serotonergic, dopaminergic, and GABAergic systems and enrichment of genes associated with synaptic function and excitatory neurons.
Hu Xu +9 more
wiley +1 more source
Author response: Vglut2-based glutamatergic signaling in central noradrenergic neurons is dispensable for normal breathing and chemosensory reflexes [PDF]
Yuan Chang +4 more
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The Ontogenetic Development of Rapid Eye Movement Sleep in Early Life and Its Regulatory Mechanisms
REM sleep was first identified in humans and cats in the late 1950s and exhibits a conserved developmental trajectory across species. This study elucidates key characteristic changes during REM sleep development, thereby providing a foundation for improving the prevention and treatment of various neurodevelopmental disorders.
Xiu‐Juan Zhang +8 more
wiley +1 more source
Noradrenergic Suppression of Persistent Firing in Hippocampal CA1 Pyramidal Cells through cAMP-PKA Pathway [PDF]
María Jesús Valero-Aracama +4 more
openalex +1 more source
Pharmacological MRI: Utility in Understanding Drug Mechanisms in Psychiatric Disorders
ABSTRACT Pharmacological MRI (pharmaMRI) has emerged as a powerful tool to study how psychoactive drugs affect brain function and to uncover mechanisms of drug action in psychiatric disorders. This review provides an overview of key techniques used in pharmaMRI, including BOLD‐fMRI, arterial spin labeling (ASL), and cerebral blood volume (CBV) mapping,
Christin Y. Sander +4 more
wiley +1 more source
Drugs of Abuse Specifically Sensitize Noradrenergic and Serotonergic Neurons Via a Non-Dopaminergic Mechanism [PDF]
Christophe Lanteri +4 more
openalex +1 more source

