Results 31 to 40 of about 2,270 (113)
The overall estimate of the percentage of deep endometriotic lesion progression over time in untreated individuals was 21.4%, whereas it was 12.4% during various hormonal treatments. The potential serious complications of uncontrolled lesion progression, such as bowel occlusion and ureteral stenosis with kidney failure should be taken into account ...
Veronica Bandini+5 more
wiley +1 more source
Current understanding on pharmacokinetics, clinical efficacy and safety of progestins for treating pain associated to endometriosis [PDF]
Introduction: Endometriosis is a chronic estrogen and progestogen responsive inflammatory disease associated with pain symptoms and infertility. The medical therapy of endometriosis aims to induce decidualization within the hormonally dependent ectopic ...
Barra, Fabio+2 more
core +1 more source
Long‐acting injectable (LAI) cabotegravir and rilpivirine for HIV treatment and LAI cabotegravir for pre‐exposure HIV prophylaxis are being rolled out in a multitude of countries worldwide. Due to the prolonged exposure, it can be challenging to undertake ‘traditional’ pharmacokinetic studies and current guidance is derived from their oral equivalents ...
Adrian Steulet+5 more
wiley +1 more source
Potential of Typha angustifolia L. in removing norethindrone from water [PDF]
Uncontrollable demand of pharmaceutical especially contraception drugs and poor performance of conventional wastewater treatment plants has resulted in the increasing concentration of pharmaceutical residues in natural environment.
Kartini Saibeh+2 more
core
Treatment of relapsed/refractory severe aplastic anemia in children: Evidence‐based recommendations
Abstract Severe aplastic anemia (SAA) is a rare potentially fatal hematologic disorder. Although overall outcomes with treatment are excellent, there are variations in management approach, including differences in treatment between adult and pediatric patients. Certain aspects of treatment are under active investigation in clinical trials.
Kristin A. Shimano+18 more
wiley +1 more source
The influence of oral contraceptives on the exercise pressor reflex in the upper and lower body
Abstract Previous research has demonstrated that oral contraceptive (OC) users have enhanced cardiorespiratory responses to arm metaboreflex activation (i.e., postexercise circulatory occlusion, PECO) and attenuated pressor responses to leg passive movement (PM) compared to non‐OC users (NOC).
T. J. Pereira, H. Edgell
wiley +1 more source
Abstract The purpose of this study was to investigate whether endothelin‐A receptor (ETAR) inhibition in non‐Hispanic Black (NHB) and White (NHW) young adults depends on biological sex. We recruited females during low hormone (n = 22) and high hormone (n = 22) phases, and males (n = 22).
Casey G. Turner+4 more
wiley +1 more source
Hydrothermal Endometrial Ablation Can Reduce the Need for Hysterectomy and Transfusion [PDF]
The authors report that hydrothermal ablation can obviate the necessity for transfusion in cases of persistent uterine bleeding secondary to large submucosal and intrauterine myomas that are resistant to medical ...
Goldfarb, Herbert A.+2 more
core +2 more sources
Abstract Fixed‐dose combination (FDC) therapies can enhance patient convenience and adherence to prescribed treatment regimens. Elagolix is a novel oral gonadotropin‐releasing hormone receptor antagonist approved for management of moderate to severe pain associated with endometriosis and heavy menstrual bleeding associated with uterine fibroids ...
Mong‐Jen Chen+5 more
wiley +1 more source
Effect of vitamin D supplementation on blood pressure:a systematic review and meta-analysis incorporating individual patient data [PDF]
D-PRESSURE Collaboration: et al.[Importance]: Low levels of vitamin D are associated with elevated blood pressure (BP) and future cardiovascular events.
Alvarez, Jessica+21 more
core +3 more sources