Results 41 to 50 of about 961 (135)
Scientific Reports, 2017 Pharmaceuticals and personal care products (PPCPs) have been found in wastewater treatment plant (WWTP) effluents and their recipient watersheds. To assess the potential of WWTP effluents to alter fish behaviour, we caged male goldfish (Carassius auratus)
D. B. D. Simmons +5 more
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The Concise Guide to PHARMACOLOGY 2025/26: Ion channels
British Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +86 more
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Neural Plasticity, 2014 Selective serotonin reuptake inhibitor medications are one of the most common treatments for mood disorders. In humans, these medications are taken orally, usually once per day. Unfortunately, administration of antidepressant medications in rodent models
Jodi L. Pawluski +6 more
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Effects of sodium fluoride on serum concentrations of selected psychotropic drugs
Journal of Forensic Sciences, Volume 70, Issue 5, Page 1939-1948, September 2025.Abstract Caution is imperative when interpreting drug concentrations in blood, plasma, or serum, given the potential variance in the distribution of a compound across these fluids. Preservatives, such as sodium fluoride, prove beneficial in preventing drug degradation in collected blood samples. This study aimed to examine the impact of sodium fluoride
Jennifer Liut +6 more
wiley +1 more source
Heliyon, 2019 Along many decades, protected environments were targeted by the scientific community for ecological research and for the collection of scientific information related to environmental aspects and biodiversity.
Esteban Avigliano +15 more
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Analytical Science Advances, Volume 6, Issue 1, June 2025.ABSTRACT Liquid chromatography–mass spectrometry (LC–MS) is a highly sophisticated analytical technique that has become indispensable for sample analysis across various scientific domains. In recent years, LC–MS has emerged as a cornerstone technology in comparative replicate sample analysis, particularly in the fields of proteomics, lipidomics and ...
Samyah Alanazi
wiley +1 more source
Ganaxolone improves behavioral deficits in a mouse model of post-traumatic stress disorder
Frontiers in Cellular Neuroscience, 2014 Allopregnanolone and its equipotent stereoisomer, pregnanolone (together termed ALLO), are neuroactive steroids that positively and allosterically modulate the action of gamma-amino-butyric acid (GABA) at GABAA receptors.
Graziano ePinna, Ann M Rasmusson
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Water and Environment Journal, Volume 39, Issue 2, Page 143-167, May 2025.Abstract Microextraction methods such as hollow fibre‐liquid phase microextraction (HF‐LPME), dispersive liquid–liquid microextraction (DLLME), single‐drop microextraction (SDME) and ultrasound‐assisted emulsification microextraction (USAEME) have become prominent for analysing pharmaceuticals in wastewater. HF‐LPME, particularly the three‐phase system,
Bavuyile Magqira, Precious Mahlambi
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Molecular Brain, 2018 Leak K+ currents are mediated by two-pore domain K+ (K2P) channels and are involved in controlling neuronal excitability. Of 15 members of K2P channels cloned so far, TRAAK, TREK-1, and TREK-2 are temperature sensitive. In the present study, we show that
Viacheslav Viatchenko-Karpinski +2 more
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Biological Reviews, Volume 100, Issue 2, Page 556-585, April 2025.ABSTRACT Behavioural analysis has been attracting significant attention as a broad indicator of sub‐lethal toxicity and has secured a place as an important subdiscipline in ecotoxicology. Among the most notable characteristics of behavioural research, compared to other established approaches in sub‐lethal ecotoxicology (e.g.
Michael G. Bertram +34 more
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