Results 31 to 40 of about 1,322 (181)
Pharmaceutics, 2023 Fluoxetine is the recommended first-line antidepressant in many therapeutic guidelines for children and adolescents. However, little is known about the relationships between drug dose and serum level as well as the therapeutic serum reference range in ...
Michael Frey +32 more
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Block of TREK and TRESK K2P channels by lamotrigine and two derivatives sipatrigine and CEN-092
Biochemistry and Biophysics Reports, 2021 TREK and TRESK K2P channels are widely expressed in the nervous system, particularly in sensory neurons, where they regulate neuronal excitability. In this study, using whole-cell patch-clamp electrophysiology, we characterise the inhibitory effect of ...
Yvonne Walsh +3 more
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Automated HPLC assay of fluoxetine and norfluoxetine in serum
Clinical Chemistry, 1994 Abstract This automated assay determines the concentration of the antidepressant fluoxetine (Prozac) and its active metabolite norfluoxetine in serum by reversed-phase HPLC with spectrophotometric detection. Extraction, injection, and quantification are performed by the Gilson Aspec automated sample handler.
J H, Nichols, J R, Charlson, G M, Lawson
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Fluoxetine does not impair motor function in patients with Parkinson's disease: Correlation between mood and motor functions with plasma concentrations of fluoxetine/norfluoxetine [PDF]
Vojnosanitetski Pregled, 2012 Background/Aim. Selective serotonin reuptake inhibitors are the most commonly chosen antidepressants in patients with Parkinson's disease (PD). The aim of our study was to assess the influence of fluoxetine (Flu) on motor functions in patients with PD.
Kostić Vladimir +12 more
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Disposition of Chiral and Racemic Fluoxetine and Norfluoxetine Across Childbearing [PDF]
Journal of Clinical Psychopharmacology, 2010 To add to the limited data on the clinical pharmacology of antidepressants during pregnancy, we examined the dose-corrected chiral and racemic levels (level/dose) of fluoxetine (FLX) and norfluoxetine (NorFLX) during pregnancy and early postpartum.The authors evaluated 17 pregnant women who received fluoxetine therapy. Doses were recorded weekly across
Dorothy, Sit +5 more
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, 2015 In this study the authors assessed the bioequivalence of two fluoxetine tablet formulations in 24 healthy volunteers of both sexes who received a single 20 mg dose of each fluoxetine formulation, and a new sensitive method for the quantification of ...
Lerner, FE +5 more
core +2 more sources
Plasma fluoxetine and norfluoxetine levels (ng/ml).
, 2013 Plasma fluoxetine and norfluoxetine levels (ng/ml).
Yumiko Ikeda (585868) +5 more
core +1 more source
Environment International, 2020 The present work aimed to discuss the enantiomeric occurrence of chiral pharmaceuticals including 5 parent compounds (PCs) metoprolol, propranolol, atenolol, venlafaxine and fluoxetine as well as 6 of their transformation products (TPs) in surface water ...
Ruixue Ma +4 more
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Inter-individual and intra-treatment variability of norfluoxetine plasma concentrations.
, 2014 The unit of the values indicated in the columns Mean, Median, Min, Max, 25%, and 75% is ng/mL.Inter-individual and intra-treatment variability of norfluoxetine plasma concentrations.
John P. Sumpter (71802) +7 more
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, 1998 The effects of intraperitoneal administration of fluoxetine (2.5, 5, 10 or 20 mg kg−1) and norfluoxetine (10 mg kg−1) on 5-hydroxytryptamine (5-HT) and 5-hydroxyindole-3-acetic acid (5-HIAA) metabolism were examined in the blood platelets and brain of ...
Chafique Younos +4 more
core +1 more source