Results 51 to 60 of about 961 (135)

Advances in Adsorbent Materials for Pharmaceutical Pollutant Removal: A Review of Occurrence, Fate, and State‐of‐the‐Art Remediation

Journal of Chemistry, Volume 2025, Issue 1, 2025.
The rise in population growth that necessitates an increase in animal husbandry activities has led to overconsumption, improper use, and disposal of pharmaceuticals such as antibiotics leading to environmental pollution. In developing countries where we have inefficient and outdated wastewater treatment facilities that are unable to effectively remove ...
Lucy Nyambura Munuhe, Edwin Shigwenya Madivoli, Dennis Mwanza Nzilu, Peter Njenga Lemeitaron, Paul Kinyanjui Kimani, Beatrice Severino   +5 more
wiley   +1 more source

Serum fluoxetine and norfluoxetine levels support the safety of fluoxetine in overdose [PDF]

Annals of General Psychiatry, 2016
Previous literature has found fluoxetine to be relatively safe in overdose. This study hopes to examine this idea along with support from published pharmacokinetic information including serum fluoxetine and norfluoxetine levels based on information from a clinical case series.Four cases are presented along with vital abnormalities, electrocardiogram ...
Stephanie Pope, Solomon G. Zaraa
openaire   +2 more sources

Automated enzymatic hydrolysis of urine samples for improved systematic toxicological analysis of drug‐facilitated sexual assault cases

Drug Testing and Analysis, Volume 16, Issue 11, Page 1254-1270, November 2024.
Development and validation of an UHPLC‐MS/MS screening method covering 144 drugs and metabolites relevant to drug‐faciliated sexual assaults. The method included an automated enzymatic hydrolysis for an improved systemtatic toxicological analysis of DFSA cases.
Kathrine Skov, Sys Stybe Johansen, Kristian Linnet, Marie Katrine Klose Nielsen   +3 more
wiley   +1 more source

Pharmaceutical Pollution of the English National Parks

Environmental Toxicology and Chemistry, Volume 43, Issue 11, Page 2422-2435, November 2024.
Image of a sewer discharging medicines into a small stream flowing through an idyllic woodland environment (generated using Wepik). Abstract England's 10 national parks are renowned for their landscapes, wildlife, and recreational value. However, surface waters in the national parks may be vulnerable to pollution from human‐use chemicals, such as ...
Alistair B. A. Boxall, Rob Collins, John L. Wilkinson, Caroline Swan, Alejandra Bouzas‐Monroy, Josh Jones, Emily Winter, Jessie Leach, Ursula Juta, Alex Deacon, Ian Townsend, Peter Kerr, Rachel Paget, Michael Rogers, Dave Greaves, Dan Turner, Caitlin Pearson   +16 more
wiley   +1 more source

The Tissue‐Specific Eco‐Exposome: Differential Pharmaceutical Bioaccumulation and Disposition in Fish among Trophic Positions

Environmental Toxicology and Chemistry, Volume 43, Issue 8, Page 1894-1902, August 2024.
Abstract Though bioaccumulation of pharmaceuticals by aquatic organisms continues to receive scientific attention, the internal disposition of these contaminants among different tissue compartments of fish species has been infrequently investigated, particularly among fish at different trophic positions. We tested a human to fish biological read‐across
Jaylen L. Sims, Alexander R. Cole, Zachary S. Moran, Charles M. Mansfield, Bianca Possamai, Macarena Rojo, Ryan S. King, Cole W. Matson, Bryan W. Brooks   +8 more
wiley   +1 more source

Fluoxetine and Norfluoxetine Revisited: New Insights into the Electrochemical and Spectroscopic Properties [PDF]

The Journal of Physical Chemistry A, 2009
The extent to which humans and wildlife are exposed to the vast array of anthropogenic chemicals and their degradation products, along with related naturally occurring compounds, is nowadays an important issue. The study of the physical-chemical properties of the compounds and/or degradation products is an important subject because some of them are ...
E Manuela, Garrido, Jorge, Garrido, Rita, Calheiros, M Paula M, Marques, Fernanda, Borges   +4 more
openaire   +3 more sources

Broad evidence of xylazine in the UK illicit drug market beyond heroin supplies: Triangulating from toxicology, drug‐testing and law enforcement

Addiction, Volume 119, Issue 7, Page 1301-1309, July 2024.
Abstract Background and aims Xylazine is a non‐opioid sedative which has spread rapidly throughout the US illicit drug supply. This study aimed to describe the spread of xylazine throughout the UK illicit drug supply. Methods Xylazine detections in human biological samples were collated from toxicology laboratories operating in the United Kingdom with ...
Caroline S. Copeland, Kathleen Rice, Kirsten L. Rock, Simon Hudson, Peter Streete, Alexander J. Lawson, Lewis Couchman, Adam Holland, Stephen Morley   +8 more
wiley   +1 more source

Programmable Delivery of Fluoxetine via Wearable Bioelectronics for Wound Healing In Vivo

Advanced Materials Technologies, Volume 9, Issue 7, April 4, 2024.
A programmable battery powered bioelectronic device delivers fluoxetine in a murine model for wound healing. Abstract The ability to deliver drugs with precise dosages at specific time points can significantly improve disease treatment while reducing side effects.
Houpu Li, Hsin‐ya Yang, Narges Asefifeyzabadi, Prabhat Baniya, Andrea Medina Lopez, Anthony Gallegos, Kan Zhu, Tiffany Nguyen, Cristian Hernandez, Ksenia Zlobina, Cynthia Recendez, Hao‐Chieh Hsieh, Maryam Tebyani, Héctor Carrión, John Selberg, Le Luo, Moyasar A. Alhamo, Alexie Barbee, Jonathan Orozco, Cathleen Hsieh, Athena M. Soulika, Michael Levin, Narges Norouzi, Marcella Gomez, Min Zhao, Mircea Teodorescu, Roslyn Rivkah Isseroff, Marco Rolandi   +27 more
wiley   +1 more source

Applications of electrophoresis for small enantiomeric drugs in real‐world samples: Recent trends and future perspectives

ELECTROPHORESIS, Volume 45, Issue 1-2, Page 55-68, January 2024.
Abstract Separation and identification of chiral molecules is a topic widely discussed in the literature and of fundamental importance, especially in the pharmaceutical and food fields, both from industrial and laboratory points of view. Several techniques are used to carry out these analyses, but high‐performance liquid chromatography is often the ...
Imran Ali, Miryam Perrucci, Luigi Ciriolo, Cristian D'Ovidio, Ugo de Grazia, Halil Ibrahim Ulusoy, Abuzar Kabir, Fabio Savini, Marcello Locatelli   +8 more
wiley   +1 more source

Anorectic activity of fluoxetine and norfluoxetine in mice, rats and guinea-pigs

Journal of Pharmacy and Pharmacology, 1992
Abstract The present study aimed to establish the role of the metabolite norfluoxetine in the anorectic activity of fluoxetine, and to relate the anorectic doses (ED50) to the brain concentrations of the parent drug and its metabolite.
M, Anelli, A, Bizzi, S, Caccia, A M, Codegoni, C, Fracasso, S, Garattini   +5 more
openaire   +2 more sources