Results 131 to 140 of about 9,073,605 (308)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Sparse Representation With Gaussian Atoms and Its Use in Anomaly Detection

open access: yesIEEE Open Journal of Signal Processing
We propose sparse representation and dictionary learning algorithms for dictionaries whose atoms are characterized by Gaussian probability distributions around some central atoms.
Denis C. Ilie-Ablachim   +2 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Caracterización de los datos de medición de armónicos variables en el tiempo; Characterization of Time Varying Harmonics Data Measurement

open access: yesRevista Científica de Ingeniería Energética, 2011
En el artículo se hace una revisión de los problemas asociados a la medición de los niveles de armónicos presentes,en una onda distorsionada de tensión y corriente no estacionaria, y se efectúa la caracterizaci ...
Vladimir Sousa Santos   +3 more
doaj  

Testing Special Cases of the GB2 Distribution: Comment and an Extension

open access: yes
We extend earlier work (Griffiths and Hill, 2025) by pointing out that a score test developed by Prentice (1975) for testing whether a normal distribution is an adequate representation of the log of a GB2 random variable is suitable for testing whether a
Hill, R. Carter, Griffiths, William
core  

The Beaman Distribution: A New Descriptive Model for the Size Distribution of Incomes

open access: yes, 2008
A new two-parameter descriptive model for the size distribution of incomes is presented. The Beaman distribution, originally found to describe the relationship between prices and sales volumes of textiles and related products, is shown to fit closely US ...
Maclachlan, Fiona C., Reith, John E.
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

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