Results 151 to 160 of about 9,073,605 (308)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Statistical Inference of Truncated Normal Distribution Based on the Generalized Progressive Hybrid Censoring. [PDF]
Entropy (Basel), 2021 Zeng X, Gui W.
europepmc +1 more source
, 2016 An economic crisis can be described as a rapid development of events manifested by sudden misallocation of resources. High percentages of bankrupt companies or financial institutions, low investment and unusually high unemployment are some examples of ...
Koulovatianos, Christos
core
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
The Impasse of Post Keynesian Distribution Theory
, 1992 Why did the topic of income distribution loose its attraction for the economic profession? The article analyzes the structure of the Ricardian theory and of the post-Keynesian approach and discusses the question why after Pasinetti’s contribution ...
Thomasberger, C.
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Using the half normal distribution to quantify covariate balance in cluster-randomized pragmatic trials. [PDF]
Trials, 2021 Huang J, Roth DL.
europepmc +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Accuracy evaluation of surface registration algorithm using normal distribution transform in stereotactic body radiotherapy/radiosurgery: A phantom study. [PDF]
J Appl Clin Med Phys, 2022 Lee H, Park JM, Kim KH, Lee DH, Sohn MJ.
europepmc +1 more source