Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Genome-wide association studies and QTL mapping for traits deviating from normal distribution. [PDF]
Natl Sci RevTang Y +7 more
europepmc +1 more source
Process capability indices in normal distribution with the presence of outliers. [PDF]
J Appl Stat, 2020 Jabbari Nooghabi M.
europepmc +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Normal distribution of bad reduction. [PDF]
Ramanujan JLemke Oliver RJ, Loughran D, Shnidman A.
europepmc +1 more source
Predictive Maintenance Scheduling with Failure Rate Described by Truncated Normal Distribution. [PDF]
Sensors (Basel), 2020 Paprocka I, Kempa WM, Ćwikła G.
europepmc +1 more source
Effective Demand and Income Distribution in The General Theory
, 1994 The paper looks at income distribution in a short-period context which is similar to that of Keynes’s General Theory. The approach to distribution is different from the one Kaldor adopted in the 1950s: no assumption of full employment is made.
Sardoni, C.
core
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Multivariate Normal Distribution Method for a Virtual Cerebral Arterial Population. [PDF]
Int J Numer Method Biomed EngJin K +6 more
europepmc +1 more source
The Early Marginalists and the Transformation of Distribution Theory
, 1992 This paper examines the roles of Jevons, Menger and Walras in transforming distribution theory from the analysis of a social issue into a subset of general price theory.
Baum, S.
core