Results 31 to 40 of about 330,857 (240)

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar   +7 more
wiley   +1 more source

Complement factors C4 and C3 are down regulated in response to short term overfeeding in healthy young men

open access: yesScientific Reports, 2017
Insulin resistance is associated with high circulating level of complement factor C3. Animal studies suggest that improper complement activation mediates high-fat-diet-induced insulin resistance.
Caroline Foghmar   +4 more
doaj   +1 more source

Dysregulation of complement system in HELLP syndrome

open access: yesHypertension in Pregnancy, 2021
Objective To investigate the expression of complement system’s activation factors in patients with HELLP syndrome. Methods A case–control study was performed. Sixteen HELLP syndrome patients, 32 severe preeclampsia patients, and 48 normal pregnancy women
Shi Chen   +3 more
doaj   +1 more source

Establishing a Case for Anti-complement Therapy in Membranous Nephropathy

open access: yesKidney International Reports, 2021
Introduction: Membranous nephropathy (MN) is a common cause of adult nephrotic syndrome that progresses to end-stage kidney disease in up to 40% of cases. It is an autoimmune disease characterized by glomerular subepithelial deposits containing IgG.
Isabelle Ayoub   +16 more
doaj   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei   +17 more
wiley   +1 more source

Normalp-complements for finite groups

open access: yesMathematische Zeitschrift, 1959
The minimal number of generators of the group Q is denoted m(s). We define d(B) = max m(s) where ‘21 ranges over all the abelian subgroups of EJ and we let J(cli) be the subgroup generated by all the abelian subgroups ‘u of (5 which satisfy d(B) = m(a). Clearly, if J(S) c R c Q, then J(B) is a characteristic subgroup of R, J(B) char Ji.
openaire   +2 more sources

Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel   +15 more
wiley   +1 more source

On the order of the Schur multiplier of a pair of finite p-groups II [PDF]

open access: yesInternational Journal of Group Theory, 2013
Let G be a finite p-group and N be a normal subgroup of G with |N|=p^n and |M|=p^m. A result of Ellis (1998) shows that the order of the Schur multiplier of such a pair (G,N) of finite p-groups is bounded by p^(1/2 n(2m+n-1)) and hence it is equal to p ...
Behrooz Mashayekhy   +2 more
doaj  

Phase Angle as an Early Functional Biomarker of Cancer‐Related Fatigue in Pediatric Oncology: A Prospective Longitudinal Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric cancer remains a leading cause of morbidity and mortality worldwide, particularly in low‐and middle‐income countries. Cancer treatment may impair nutritional status, alter body composition, and exacerbate cancer‐related fatigue (CRF).
Luís Carlos Lopes‐Junior   +11 more
wiley   +1 more source

Alterations of Plasma Galectin-3 and C3 Levels in Patients with Parkinson’s Disease

open access: yesBrain Sciences, 2021
Parkinson’s disease (PD) is characterized by progressive neurodegeneration of dopaminergic neurons in the ventral midbrain. The complement-phagosome pathway is involved in the pathogenesis of PD.
Hsiu-Chuan Wu   +3 more
doaj   +1 more source

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