Results 41 to 50 of about 838,377 (285)

Complement factors C4 and C3 are down regulated in response to short term overfeeding in healthy young men

open access: yesScientific Reports, 2017
Insulin resistance is associated with high circulating level of complement factor C3. Animal studies suggest that improper complement activation mediates high-fat-diet-induced insulin resistance.
Caroline Foghmar   +4 more
doaj   +1 more source

Normalp-complements for finite groups

open access: yesMathematische Zeitschrift, 1959
The minimal number of generators of the group Q is denoted m(s). We define d(B) = max m(s) where ‘21 ranges over all the abelian subgroups of EJ and we let J(cli) be the subgroup generated by all the abelian subgroups ‘u of (5 which satisfy d(B) = m(a). Clearly, if J(S) c R c Q, then J(B) is a characteristic subgroup of R, J(B) char Ji.
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Leptospira interrogans endostatin-like outer membrane proteins bind host fibronectin, laminin and regulators of complement

open access: yes, 2007
The pathogenic spirochete Leptospira interrogans disseminates throughout its hosts via the bloodstream, then invades and colonizes a variety of host tissues.
Matthew L Rotondi   +54 more
core   +1 more source

Innate immunity and neuroinflammation [PDF]

open access: yes, 2013
Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Kishore, U   +5 more
core   +1 more source

On the order of the Schur multiplier of a pair of finite p-groups II [PDF]

open access: yesInternational Journal of Group Theory, 2013
Let G be a finite p-group and N be a normal subgroup of G with |N|=p^n and |M|=p^m. A result of Ellis (1998) shows that the order of the Schur multiplier of such a pair (G,N) of finite p-groups is bounded by p^(1/2 n(2m+n-1)) and hence it is equal to p ...
Behrooz Mashayekhy   +2 more
doaj  

The Complement System Is Critical in Maintaining Retinal Integrity during Aging

open access: yesFrontiers in Aging Neuroscience, 2018
The complement system is a key component of innate immunity comprised of soluble components that form a proteolytic cascade leading to the generation of effector molecules involved in cellular clearance.
Ryo Mukai   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Complement component C3 binds to activated normal platelets without preceding proteolytic activation and promotes binding to complement receptor 1

open access: yes, 2010
It has been reported that complement is activated on the surface of activated platelets, despite the presence of multiple regulators of complement activation. To reinvestigate the mechanisms by which activated platelets bind to complement components, the
Nilsson Ekdahl, Kristina,   +12 more
core   +1 more source

Alterations of Plasma Galectin-3 and C3 Levels in Patients with Parkinson’s Disease

open access: yesBrain Sciences, 2021
Parkinson’s disease (PD) is characterized by progressive neurodegeneration of dopaminergic neurons in the ventral midbrain. The complement-phagosome pathway is involved in the pathogenesis of PD.
Hsiu-Chuan Wu   +3 more
doaj   +1 more source

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