Results 71 to 80 of about 679,648 (296)

Discriminative Learning for Alzheimer’s Disease Diagnosis via Canonical Correlation Analysis and Multimodal Fusion

Frontiers in Aging Neuroscience, 2016
To address the challenging task of diagnosing neurodegenerative brain disease, such as Alzheimer’s disease (AD) and mild cognitive impairment (MCI), we propose a novel method using discriminative feature learning and canonical correlation analysis (CCA ...
Baiying eLei, Siping eChen, Dong eNi, Tianfu eWang   +3 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Uncovering prostate cancer aggressiveness signal in T2‐weighted MRI through a three‐reference tissues normalization technique

, 2023
Ahmad Algohary, Evangelia I. Zacharaki, Adrian Breto, Mohammad Alhusseini, Veronica Wallaengen, Isaac Xu, Sandra M. Gaston, Sanoj Punnen, Patricia Castillo, Pradip M. Pattany, Oleksandr N. Kryvenko, Benjamin Spieler, Matthew C. Abramowitz, Alan Dal Pra, John C. Ford, Alan Pollack, Radka Stoyanova   +16 more
openalex   +1 more source

Normalized Latent Measure Factor Models [PDF]

, 2022
Mario Beraha, Jim E. Griffin
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Discovery of the Consistently Well-Performed Analysis Chain for SWATH-MS Based Pharmacoproteomic Quantification

Frontiers in Pharmacology, 2018
Sequential windowed acquisition of all theoretical fragment ion mass spectra (SWATH-MS) has emerged as one of the most popular techniques for label-free proteome quantification in current pharmacoproteomic research.
Jianbo Fu, Jing Tang, Jing Tang, Yunxia Wang, Xuejiao Cui, Xuejiao Cui, Qingxia Yang, Qingxia Yang, Jiajun Hong, Xiaoxu Li, Xiaoxu Li, Shuang Li, Shuang Li, Yuzong Chen, Weiwei Xue, Feng Zhu, Feng Zhu   +16 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Normalizers and self-normalizing subgroups II

Open Mathematics, 2011
Abstract Let $\mathbb{K}$ be a field, G a reductive algebraic $\mathbb{K}$-group, and G 1 ≤ G a reductive subgroup. For G 1 ≤ G, the corresponding groups of $\mathbb{K}$-points, we study the normalizer N = N G(G 1).
openaire   +4 more sources

Validation and Normalization of Grasha–Riechmann Teaching Style Inventory in Faculty Members of Zahedan University of Medical Sciences

Advances in Medical Education and Practice, 2020
Azizollah Arbabisarjou,1 Maryam Akbarilakeh,2 Fatemeh Soroush,3 Abolfazl Payandeh4 1Department of Nursing Management, Zahedan University of Medical Sciences, Zahedan, Iran; 2Department of Medical Education, School of Management and Medical Education ...
Arbabisarjou A, Akbarilakeh M, Soroush F, Payandeh A   +3 more
doaj  

Troubleshooting in Large-Scale LC-ToF-MS Metabolomics Analysis: Solving Complex Issues in Big Cohorts

Metabolites, 2019
Metabolomics, understood as the science that manages the study of compounds from the metabolism, is an essential tool for deciphering metabolic changes in disease.
Juan Rodríguez-Coira, María I Delgado-Dolset, David Obeso, Mariana Dolores-Hernández, Guillermo Quintás, Santiago Angulo, Domingo Barber, Teresa Carrillo, María M. Escribese, Alma Villaseñor   +9 more
doaj   +1 more source