Results 81 to 90 of about 864,283 (303)
Histograms of log2 of read counts by study indicate improved distribution overlap following normalization. A) Results without normalization applied. B) Results after applying Relative Log Expression (RLE) normalization.
Elizabeth M. McNeill (8592222) +3 more
core +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Silence and Denial in Everyday Life—The Case of Animal Suffering
How can we make sense of the fact that we live in a world where good people co-exist in silence about widespread animal suffering. How is it that sites of suffering such as laboratories, factory farms, abattoirs and animal transportation are all around ...
Deidre Wicks
doaj +1 more source
jcreinhold/intensity-normalization: Tarantula - v1.1
intensity-normalization v1.1 release notes Quality Metric <p>Added a quality metric for the normalization result (pairwise calculation of Jensen-Shannon Divergence of the histograms) and created a corresponding plotting routine to visualize the ...
Jacob Reinhold
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Conceptual normalization of senar terminological neologisms [PDF]
: Terminologies’ Conceptual Normalization (P. I. Coulibaly, 2018, p. 429), a linguistic approach of terminology normalization within the theoretical framework of optimal terminology (P. I. Coulibaly, 2016) is based on the morphological (K. O.
ASSANVO Amoikon Dyhie +1 more
doaj
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Synthetic aperture radar (SAR) applications often require normalization to a common incidence angle. Angular signatures of radar backscatter depend on surface roughness and vegetation cover, and thus differ, from location to location.
Barbara Widhalm +2 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Developing WASPAS-RTB method for range target-based criteria: toward selection for robust design
Recently, considerable attention has been devoted to application of multi-attribute decision-making (MADM) method in materials selection. Normalization can be considered as a foundation for rational MADM methods, which should deal with target-based ...
Ali Jahan
doaj +1 more source

