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The Gene Ontology's Reference Genome Project: a unified framework for functional annotation across species. [PDF]
PLoS Computational Biology, 2009 The Gene Ontology (GO) is a collaborative effort that provides structured vocabularies for annotating the molecular function, biological role, and cellular location of gene products in a highly systematic way and in a species-neutral manner with the aim ...
Reference Genome Group of the Gene Ontology Consortium
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iRGvalid: A Robust in silico Method for Optimal Reference Gene Validation
Frontiers in Genetics, 2021 BackgroundAppropriate reference genes are critical to accurately quantifying relative gene expression in research and clinical applications. Numerous efforts have been made to select the most stable reference gene(s), but a consensus has yet to be ...
Zhongxu Zhu, Keqin Gregg, Wenli Zhou
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Identification of the Optimal Quantitative RT-PCR Reference Gene for Paper Mulberry (Broussonetia papyrifera) [PDF]
Current Issues in Molecular BiologyPaper Mulberry (Broussonetia papyrifera) possesses medicinal, economic, and ecological significance and is extensively used for feed production, papermaking, and ecological restoration due to its ease of propagation, rapid growth rate, and strong stress ...
Fangwei Zhou +4 more
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Evaluation of Suitable Reference Gene During the Development of Paired or Unpaired Female Schistosoma japonicum on the 18th and the 23rd Days Post Infection [PDF]
PathogensBackground: Identifying optimal housekeeping genes is essential to accurately quantify gene expression dynamics across the 18th day (male and female begin to pair) and the 23rd day (female begin to sex mature) post infection of Schistosoma japonicum ...
Suwen Wang, Liang Feng, Jun Sun
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Infectious Agents and Cancer, 2022 Background Sexually transmitted infections (STIs) are prevalent throughout the world and impose a significant burden on individual health and public health systems.
Zhihai Ma +12 more
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Frontiers in Physiology, 2022 RT-qPCR remains a vital approach for molecular biology studies aimed at quantifying gene expression in a range of physiological or pathological settings.
Zixin Liu +8 more
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Housekeeping Genes for Parkinson’s Disease in Humans and Mice
Cells, 2021 A critical aspect of real-time PCR is the presence of housekeeping genes (HKGs) as an internal control for the normalization of expression data for genes of interest.
Anelya Kh. Alieva +4 more
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Frontiers in Physiology, 2021 Rhopalosiphum padi (L.) (Hemiptera: Aphididae) is an important cosmopolitan pest in cereal crops. Reference genes can significantly affect qRT-PCR results. Therefore, selecting appropriate reference genes is a key prerequisite for qRT-PCR analyses.
Mengyi Li +16 more
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Frontiers in Physiology, 2021 Ips sexdentatus (Coleoptera: Curculionidae: Scolytinae) is one of the most destructive and economically important forest pests. A better understanding of molecular mechanisms underlying its adaptation to toxic host compounds may unleash the potential for
Gothandapani Sellamuthu +9 more
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Visualizing Viral Infection In Vivo by Multi-Photon Intravital Microscopy
Viruses, 2018 Viral pathogens have adapted to the host organism to exploit the cellular machinery for virus replication and to modulate the host cells for efficient systemic dissemination and immune evasion.
Xaver Sewald
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