Results 31 to 40 of about 7,761,125 (307)

Update on Viral Gene Therapy Clinical Trials for Retinal Diseases [PDF]

, 2022
In 2001, the first large animal was successfully treated with a gene therapy that restored its vision. Lancelot, the Briard dog that was treated, suffered from a human childhood blindness called Leber's congenital amaurosis type 2.
Cheng, Shun-Yun, Punzo, Claudio
core   +1 more source

Effect of Savirin or Ticagrelor Treatment on the Expression of Commonly Used Reference Genes in Staphylococcus aureus

Microorganisms, 2023
Reference genes are frequently used for the normalization of quantitative reverse transcriptase PCR (qRTPCR) data in gene expression studies. Staphylococcus aureus is one of the most common causes of biofilm-related infections.
Narayan Pant, Catherine Rush, Jeffrey Warner, Damon P. Eisen   +3 more
doaj   +1 more source

A reference gene catalogue of the pig gut microbiome [PDF]

Nature Microbiology, 2016
The pig is a major species for livestock production and is also extensively used as the preferred model species for analyses of a wide range of human physiological functions and diseases1. The importance of the gut microbiota in complementing the physiology and genome of the host is now well recognized2.
Liang Xiao, Jordi Estellé, Pia Kiilerich, Yuliaxis Ramayo-Caldas, Zhongkui Xia, Qiang Feng, Suisha Liang, Anni Øyan Pedersen, Niels Jørgen Kjeldsen, Chuan Liu, Emmanuelle Maguin, Joël Doré, Nicolas Pons, Emmanuelle Le Chatelier, Edi Prifti, Junhua Li, Huijue Jia, Xin Liu, Xun Xu, Stanislav D. Ehrlich, Lise Madsen, Karsten Kristiansen, Claire Rogel-Gaillard, Jun Wang   +23 more
openaire   +5 more sources

Reference Gene Selection for qRT-PCR Normalization Analysis in kenaf (Hibiscus cannabinus L.) under Abiotic Stress and Hormonal Stimuli

Frontiers in Plant Science, 2017
Kenaf (Hibiscus cannabinus L.), an environmental friendly and economic fiber crop, has a certain tolerance to abiotic stresses. Identification of reliable reference genes for transcript normalization of stress responsive genes expression by quantitative ...
Xiaoping Niu, Meixia Chen, Meixia Chen, Xinyu Huang, Huihuang Chen, Aifen Tao, Jiantang Xu, Jianmin Qi   +7 more
doaj   +1 more source

Selection of reference genes for RT‐qPCR normalization in blueberry (Vaccinium corymbosum × angustifolium) under various abiotic stresses

FEBS Open Bio, 2020
As a small fruit rich in anthocyanins, blueberry (Vaccinium corymbosum × angustifolium) has become a focus of research in recent years for identifying genes related to anthocyanin transport and stress resistance mechanisms based on transcriptome ...
Yu Deng, Yadong Li, Haiyue Sun
doaj   +1 more source

Reliable reference genes for gene expression analyses under the hypomagnetic field in a migratory insect

Frontiers in Physiology, 2022
Manipulating the hypomagnetic field (HMF), which is the absence or significant weakening (<5 μT) of the geomagnetic field (GMF), offers a unique tool to investigate magnetic field effects on organismal physiology, development, behavior and life ...
Ying Zhang, Ying Zhang, Luying Zeng, Luying Zeng, Yongji Wei, Yongji Wei, Ming Zhang, Ming Zhang, Weidong Pan, Gregory A. Sword, Fei Yang, Fajun Chen, Fajun Chen, Guijun Wan, Guijun Wan   +14 more
doaj   +1 more source

Reference-based QUantification Of gene Dispensability (QUOD) [PDF]

Plant Methods, 2020
Abstract Background Dispensability of genes in a phylogenetic lineage, e.g. a species, genus, or higher-level clade, is gaining relevance as most genome sequencing projects move to a pangenome level.
Frey, Katharina, Weisshaar, Bernd, Pucker, Boas   +2 more
openaire   +4 more sources

Selection of potential reference genes for RT-qPCR in the plant pathogenic fungus Colletotrichum fructicola

Frontiers in Microbiology, 2022
Colletotrichum is widespread, and these pathogenic fungi can cause various plant diseases. Studies have shown that Colletotrichum fructicola cause oil-tea (Camellia oleifera) anthracnose and is widely distributed as a dominant fungus in all Ca.
Xingzhou Chen, Xingzhou Chen, Xingzhou Chen, Xinggang Chen, Xinggang Chen, Xinggang Chen, Qian Tan, Qian Tan, Qian Tan, Yuan He, Yuan He, Yuan He, Zhikai Wang, Zhikai Wang, Zhikai Wang, Guoying Zhou, Guoying Zhou, Guoying Zhou, Junang Liu, Junang Liu, Junang Liu   +20 more
doaj   +1 more source

PPIA, HPRT1, and YWHAZ are suitable reference genes for quantitative polymerase chain reaction assay of the hypothalamic–pituitary–gonadal axis in sows [PDF]

Animal Bioscience, 2022
Objective The quantitative reverse transcription polymerase chain reaction (qPCR) is the most accurate and reliable technique for analysis of gene expression.
Hwan-Deuk Kim, Chan-Hee Jo, Yong-Ho Choe, Hyeon-Jeong Lee, Min Jang, Seul-Gi Bae, Sung-Ho Yun, Sung-Lim Lee, Gyu-Jin Rho, Seung-Joon Kim, Won-Jae Lee   +10 more
doaj   +1 more source

Validation of reference genes in human chordoma

Surgical Neurology International, 2017
Chordoma are rare slow-growing tumors of the axial skeleton, which are thought to arise from remnants of the notochord. Little is known about the underlying mechanisms that drive this tumor. However, the assessment of gene expression levels by quantitative real-time polymerase chain reaction (qRT-PCR) is hampered due to a lack of validated reference ...
Santegoeds, R G C, Yakkioui, Y, Jahanshahi, A, Hoogland, G, Temel, Y, van Overbeeke, J J   +5 more
openaire   +3 more sources