Results 71 to 80 of about 670,896 (267)

Developing WASPAS-RTB method for range target-based criteria: toward selection for robust design

open access: yesTechnological and Economic Development of Economy, 2018
Recently, considerable attention has been devoted to application of multi-attribute decision-making (MADM) method in materials selection. Normalization can be considered as a foundation for rational MADM methods, which should deal with target-based ...
Ali Jahan
doaj   +1 more source

Validation of Suitable Reference Genes for Gene Expression Studies on Yak Testis Development

open access: yesAnimals, 2020
Testis has an important function in male reproduction. Its development is regulated by a large number of genes. The real-time reserve transcriptase-quantitative polymerase chain reaction (RT-qPCR) is a useful tool to evaluate the gene expression levels ...
Xuelan Zhou   +9 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Discriminative Learning for Alzheimer’s Disease Diagnosis via Canonical Correlation Analysis and Multimodal Fusion

open access: yesFrontiers in Aging Neuroscience, 2016
To address the challenging task of diagnosing neurodegenerative brain disease, such as Alzheimer’s disease (AD) and mild cognitive impairment (MCI), we propose a novel method using discriminative feature learning and canonical correlation analysis (CCA ...
Baiying eLei   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Normalization of rings

open access: yesJournal of Symbolic Computation, 2010
We present a new algorithm to compute the integral closure of a reduced Noetherian ring in its total ring of fractions. A modification, applicable in positive characteristic, where actually all computations are over the original ring, is also described.
Greuel, G.-M.   +2 more
openaire   +6 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Discovery of the Consistently Well-Performed Analysis Chain for SWATH-MS Based Pharmacoproteomic Quantification

open access: yesFrontiers in Pharmacology, 2018
Sequential windowed acquisition of all theoretical fragment ion mass spectra (SWATH-MS) has emerged as one of the most popular techniques for label-free proteome quantification in current pharmacoproteomic research.
Jianbo Fu   +16 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Validation and Normalization of Grasha–Riechmann Teaching Style Inventory in Faculty Members of Zahedan University of Medical Sciences

open access: yesAdvances in Medical Education and Practice, 2020
Azizollah Arbabisarjou,1 Maryam Akbarilakeh,2 Fatemeh Soroush,3 Abolfazl Payandeh4 1Department of Nursing Management, Zahedan University of Medical Sciences, Zahedan, Iran; 2Department of Medical Education, School of Management and Medical Education ...
Arbabisarjou A   +3 more
doaj  

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