Results 51 to 60 of about 1,695,800 (292)

Normal Extensions

open access: yesFormalized Mathematics, 2023
Summary In this article we continue the formalization of field theory in Mizar [1], [2], [4], [3]. We introduce normal extensions: an (algebraic) extension E of F is normal if every polynomial of F that has a root in E already splits in E.
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Tumor Hypoxia Regulates Immune Escape/Invasion: Influence on Angiogenesis and Potential Impact of Hypoxic Biomarkers on Cancer Therapies

open access: yesFrontiers in Immunology, 2021
The environmental and metabolic pressures in the tumor microenvironment (TME) play a key role in molding tumor development by impacting the stromal and immune cell fractions, TME composition and activation.
Raefa Abou Khouzam   +10 more
doaj   +1 more source

Two-Stage Document Length Normalization for Information Retrieval

open access: yes, 2015
The standard approach for term frequency normalization is based only on the document length. However, it does not distinguish the verbosity from the scope, these being the two main factors determining the document length.
Na, Seung-Hoon
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Identifying differential transcription factor binding in ChIP-seq

open access: yesFrontiers in Genetics, 2015
ChIP seq is a widely used assay to measure genome-wide protein binding. The decrease in costs associated with sequencing has led to a rise in the number of studies that investigate protein binding across treatment conditions or cell lines. In addition to
Dai-Ying eWu   +3 more
doaj   +1 more source

MoNoise: Modeling Noise Using a Modular Normalization System [PDF]

open access: yes, 2017
We propose MoNoise: a normalization model focused on generalizability and efficiency, it aims at being easily reusable and adaptable. Normalization is the task of translating texts from a non- canonical domain to a more canonical domain, in our case ...
van der Goot, Rob, van Noord, Gertjan
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Adaptive scenario-based multi-criteria approach to assessing investment potential in agribusiness

open access: yesπ-Economy
This paper presents a comparative analysis of SAW, TOPSIS, and GDR multi-criteria aggregation methods, applied to the construction of a synthetic investment attractiveness index (SIAI). The relevance of this study is determined by the need to enhance the
Bernagrt Bella, Popova Elena
doaj   +1 more source

Research on Improving the Prediction Accuracy of Build-up Rate Based on Kriging Method

open access: yesShiyou jixie, 2023
The traditional build-up rate prediction methods in the drilling industry have some shortcomings,such as low prediction accuracy using geometric method and high computational complexity using mechanical method,which indirectly increase drilling costs ...
Pan Yongbo   +3 more
doaj  

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