Results 61 to 70 of about 765,441 (312)

jcreinhold/intensity-normalization: Tarantula - v1.1

open access: yes, 2018
intensity-normalization v1.1 release notes Quality Metric <p>Added a quality metric for the normalization result (pairwise calculation of Jensen-Shannon Divergence of the histograms) and created a corresponding plotting routine to visualize the ...
Jacob Reinhold
core   +1 more source

Normalization of EMG Signals: To Normalize or Not to Normalize and What to Normalize to?

open access: yes, 2012
© 2012 Halaki and Ginn, licensee InTech. This is an open access chapter distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Mark Halaki, Karen Gi
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tumor Hypoxia Regulates Immune Escape/Invasion: Influence on Angiogenesis and Potential Impact of Hypoxic Biomarkers on Cancer Therapies

open access: yesFrontiers in Immunology, 2021
The environmental and metabolic pressures in the tumor microenvironment (TME) play a key role in molding tumor development by impacting the stromal and immune cell fractions, TME composition and activation.
Raefa Abou Khouzam   +10 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Identifying differential transcription factor binding in ChIP-seq

open access: yesFrontiers in Genetics, 2015
ChIP seq is a widely used assay to measure genome-wide protein binding. The decrease in costs associated with sequencing has led to a rise in the number of studies that investigate protein binding across treatment conditions or cell lines. In addition to
Dai-Ying eWu   +3 more
doaj   +1 more source

Normal Extensions

open access: yesFormalized Mathematics, 2023
Summary In this article we continue the formalization of field theory in Mizar [1], [2], [4], [3]. We introduce normal extensions: an (algebraic) extension E of F is normal if every polynomial of F
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Adaptive scenario-based multi-criteria approach to assessing investment potential in agribusiness

open access: yesπ-Economy
This paper presents a comparative analysis of SAW, TOPSIS, and GDR multi-criteria aggregation methods, applied to the construction of a synthetic investment attractiveness index (SIAI). The relevance of this study is determined by the need to enhance the
Bernagrt Bella, Popova Elena
doaj   +1 more source

Research on Improving the Prediction Accuracy of Build-up Rate Based on Kriging Method

open access: yesShiyou jixie, 2023
The traditional build-up rate prediction methods in the drilling industry have some shortcomings,such as low prediction accuracy using geometric method and high computational complexity using mechanical method,which indirectly increase drilling costs ...
Pan Yongbo   +3 more
doaj  

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