Results 61 to 70 of about 1,695,800 (292)

Absolute quantitation of microbes using 16S rRNA gene metabarcoding: A rapid normalization of relative abundances by quantitative PCR targeting a 16S rRNA gene spike‐in standard

MicrobiologyOpen, 2020
Metabarcoding of the 16S rRNA gene is commonly used to characterize microbial communities, by estimating the relative abundance of microbes. Here, we present a method to retrieve the concentrations of the 16S rRNA gene per gram of any environmental ...
Olivier Zemb, Caroline S. Achard, Jerome Hamelin, Marie‐Léa De Almeida, Béatrice Gabinaud, Laurent Cauquil, Lisanne M.G. Verschuren, Jean‐Jacques Godon   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Assessing tree species diversity in forest ecosystems: A new approach

Frontiers in Ecology and Evolution, 2022
The significance of biodiversity research is to understand the structure and function of the community, and then to protect and monitor the community. The metric of biodiversity is the base of biodiversity conservation.
Zhonghua Zhao, Gangying Hui, Aimin Yang, Gongqiao Zhang, Yanbo Hu   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Sırbistan-Kosova İlişkilerinin Normalleşmesinde Avrupa Birliği’nin Rolü

Uluslararası Ekonomi, İşletme ve Politika Dergisi
Bu makalenin amacı Sırbistan-Kosova ilişkilerinin normalleşmesinde Avrupa Birliği’nin (AB) nasıl bir rol oynadığını incelemektir. Çalışma, öncelikle, Sırbistan’da Avrupalılaşma fikrinin zayıf olması ve pek olumlu olmaması, Milošević rejiminin ...
Mehmet Bardakcı
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Using Fuzzy Logic to Evaluate Normalization Completeness for An Improved Database Design

, 2012
A new approach, to measure normalization completeness for conceptual model, is introduced using quantitative fuzzy functionality in this paper. We measure the normalization completeness of the conceptual model in two steps.
Iqbal, Nayyar, Qureshi, M. Rizwan Jameel, Sharif, Mehboob   +2 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Matrix approach to consistency of the additive efficient normalization of semivalues [PDF]

, 2007
In fact the Shapley value is the unique efficient semivalue. This motivated Ruiz et al. to do additive efficient normalization for semivalues. In this paper, by matrix approach we derive the relationship between the additive efficient normalization of ...
Driessen, T.S.H., Sun, H., Xu, G.
core   +2 more sources

NormFace: L2 Hypersphere Embedding for Face Verification

, 2017
Thanks to the recent developments of Convolutional Neural Networks, the performance of face verification methods has increased rapidly. In a typical face verification method, feature normalization is a critical step for boosting performance.
Cheng, Jian, Wang, Feng, Xiang, Xiang, Yuille, Alan L.   +3 more
core   +1 more source