Results 91 to 100 of about 1,695,800 (292)

Discovery of the Consistently Well-Performed Analysis Chain for SWATH-MS Based Pharmacoproteomic Quantification

open access: yesFrontiers in Pharmacology, 2018
Sequential windowed acquisition of all theoretical fragment ion mass spectra (SWATH-MS) has emerged as one of the most popular techniques for label-free proteome quantification in current pharmacoproteomic research.
Jianbo Fu   +16 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Validation and Normalization of Grasha–Riechmann Teaching Style Inventory in Faculty Members of Zahedan University of Medical Sciences

open access: yesAdvances in Medical Education and Practice, 2020
Azizollah Arbabisarjou,1 Maryam Akbarilakeh,2 Fatemeh Soroush,3 Abolfazl Payandeh4 1Department of Nursing Management, Zahedan University of Medical Sciences, Zahedan, Iran; 2Department of Medical Education, School of Management and Medical Education ...
Arbabisarjou A   +3 more
doaj  

Troubleshooting in Large-Scale LC-ToF-MS Metabolomics Analysis: Solving Complex Issues in Big Cohorts

open access: yesMetabolites, 2019
Metabolomics, understood as the science that manages the study of compounds from the metabolism, is an essential tool for deciphering metabolic changes in disease.
Juan Rodríguez-Coira   +9 more
doaj   +1 more source

Normalizers and self-normalizing subgroups II

open access: yesOpen Mathematics, 2011
Abstract Let $\mathbb{K}$ be a field, G a reductive algebraic $\mathbb{K}$-group, and G 1 ≤ G a reductive subgroup. For G 1 ≤ G, the corresponding groups of $\mathbb{K}$-points, we study the normalizer N = N G(G 1).
openaire   +4 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Résidencialization urbaine: seguridad espacial y normalización social en las periferias sensibles francesas

open access: yesCiudades, 2018
This article will discuss the residentialization of French peripheries, an urban renewal process based on the replacement of large groups of social housing by small, closed residential units.
Noel Antonio Manzano Gómez
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

The Abiding Exceptionalism of Foreign Relations Doctrine [PDF]

open access: yes, 2015
In their article The Normalization of Foreign Relations Law, Professors Ganesh Sitaraman and Ingrid Wuerth argue that “[foreign affairs] exceptionalism . . . is now exceptional,” and that this is a good thing.
Vázquez, Carlos Manuel
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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