Results 111 to 120 of about 8,131,330 (355)

A METHOD FOR THE SOLUTION OF NORMAL EQUATIONS

open access: yesThe Journal of Agriculture of the University of Puerto Rico, 1944
A new method of solving normal equations is presented. A comparison is made of the application of the method to a multiple regression case used by Dwyer to illustrate his abbreviation of the Doolittle method. The proposed method for relatively, small numbers of unknowns at least, is simpler than Dwyer's method, considered to date to be one, if not the ...
openaire   +2 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Normalized homoclinic solutions of discrete nonlocal double phase problems

open access: yesBulletin of Mathematical Sciences
The aim of this paper is to discuss the existence of normalized solutions to the following nonlocal double phase problems driving by the discrete fractional Laplacian: ( − Δ𝔻)pαu(k) + μ(−Δ 𝔻)qβu(k) + ω(k)|u(k)|p−2u(k) = λ|u(k)|q−2u(k) + h(k)|u(k)|r−2u(k)
Mingqi Xiang, Yunfeng Ma, Miaomiao Yang
doaj   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Dunkl-Poisson Equation and Related Equations in Superspace

open access: yesMathematical Modelling and Analysis, 2015
In this paper, we investigate the Almansi expansion for solutions of Dunkl-polyharmonic equations by the 0-normalized system for the Dunkl-Laplace operator in superspace.
Hong Fen Yuan, Valery V. Karachik
doaj   +1 more source

Existence and uniqueness of normalized solutions for the Kirchhoff equation

open access: yesApplied Mathematics Letters, 2017
For a class of Kirchhoff functional, we first give a complete classification with respect to the exponent $p$ for its $L^2$-normalized critical points, and show that the minimizer of the functional, if exists, is unique up to translations. Secondly, we search for the mountain pass type critical point for the functional on the $L^2$-normalized manifold,
Yimin Zhang, Xiaoyu Zeng
openaire   +3 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Positive Normalized Solutions to a Kind of Fractional Kirchhoff Equation with Critical Growth

open access: yesFractal and Fractional
In this paper, we have investigated the existence of normalized solutions for a class of fractional Kirchhoff equations involving nonlinearity and critical nonlinearity. The nonlinearity satisfies L2-supercritical conditions.
Shiyong Zhang, Qiongfen Zhang
doaj   +1 more source

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