Results 111 to 120 of about 994,574 (330)
The effect of sodium citrate 4% locking solution for central venous dialysis catheter on the international normalized ratio (INR) value [PDF]
, 2008 Julien Rioux +3 more
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Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
AIMS MathematicsIn this paper, we study normalized solutions of the fractional Schrödinger equation with a critical nonlinearity$ \begin{eqnarray*} \left\{ \begin{array}{lll} (-\Delta)^su = \lambda u+|u|^{p-2}u+|u|^{2^\ast_s-2}u, & x\in \mathbb{R}^N, \\ \int_ ...
Xizheng Sun, Zhiqing Han
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Regularity of solutions of the parabolic normalized p-Laplace equation
Advances in Nonlinear Analysis, 2018 The parabolic normalized p-Laplace equation is studied. We prove that a viscosity solution has a time derivative in the sense of Sobolev belonging locally to L2{L^{2}}.
Høeg Fredrik Arbo, Lindqvist Peter
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Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Minimum-time acceleration of aircraft turbofan engines [PDF]
Minimum-time accelerations of the F100 turbofan engine are presented. A piecewise-linear engine model, having three state variables and four control variables, is used to obtain the minimum-time solutions.
Teren, F.
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Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Multiplicity of normalized semi-classical states for a class of nonlinear Choquard equations
Advances in Nonlinear AnalysisThis article is concerned with the existence of multiple normalized solutions for a class of Choquard equations with a parametric perturbation −ε2Δu+V(x)u=λu+ε−α(Iα*F(u))f(u),x∈RN,∫RN∣u∣2dx=a2εN,\left\{\begin{array}{ll}-{\varepsilon }^{2}\Delta u+V\left ...
Wu Jinxia, He Xiaoming
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