Results 81 to 90 of about 2,877,363 (151)

Xenogeneic, extracorporeal liver perfusion in primates improves the ratio of branched-chain amino acids to aromatic amino acids (Fischer's ratio) [PDF]

, 1999
In fulminant hepatic failure (FHF), the development of hepatic encephalopathy is associated with grossly abnormal concentrations of plasma amino acids (PAA).
Puhl, G., Neuhaus, P., Schön, M. R., Hammer, C., Matthes, M., Heil, W., Lemmens, H.-P., Padval, D.   +7 more
core   +1 more source

Developing bioethical and regulatory frameworks for research in thoracoabdominal normothermic regional perfusion

JME Practical Bioethics
Heart transplantation remains the gold standard of treatment for end-stage cardiovascular disease, but there is a persistent mismatch between the supply of donor hearts and recipient demand.
Brendan Parent, Justin Tao Wang
doaj   +1 more source

Overcoming Lung Challenges in TA-NRP Assisted Heart Recovery in Donation After the Circulatory Determination of Death

Transplant International
Thoraco-abdominal normothermic regional perfusion (TA-NRP), utilizing Extra Corporeal Membrane Oxygenation (ECMO) devices, has emerged as an effective strategy for heart recovery in donors declared dead by circulatory criteria (DCDD).
Mario Royo-Villanova, José Moya Sánchez, Alejandro Ortín Freire, Jose H. De Gea García, Sergio Rebollo Acebes, Alba Moreno Flores, Juan Blanco Morillo, Sergio Cánovas, Beatriz Domínguez-Gil   +8 more
doaj   +1 more source

Normothermic Machine Perfusion (NMP) Inhibits Proinflammatory Responses in the Liver and Promotes Regeneration

, 2019
Liver transplantation (LT) is a successful treatment for patients with liver failure. However, organ shortage results in over 11% of patients losing their chance of a transplant attributed to liver decompensation (LD) and death.
Jassem, W., Xystrakis, E., Sanchez-Fueyo, A., Lozano, J.J., Jabri, Y., Huang, X., Ma, Y., Coussios, C.C., Rela, M., Martinez-Llordella, M., Quaglia, A., Ghnewa, Y.G., Yuksel, M., Friend, P., Heaton, N., Pop, O.   +15 more
core   +1 more source

Logistics for expanding heart transplantation from donation after circulatory death using normothermic regional perfusionCentral Message

JTCVS Techniques, 2022
Nader Moazami, MD, Deane Smith, MD, Aubrey Galloway, MD   +2 more
doaj   +1 more source

Graft survival and delayed graft function with normothermic regional perfusion and rapid recovery after circulatory death in kidney transplantation: a propensity score matching study

, 2023
BACKGROUND: A shortage of kidney grafts has led to the implementation of various strategies, including donations after circulatory death. The in situ normothermic regional perfusion technique has been introduced to improve graft quality by reducing warm ...
Chamorro, L. (Laura), Salguero, J. (Joseba), Gómez-Gómez, E. (Enrique), Robles-Garcia, J.E. (José Enrique), Campos, J. P. (Juan P.)   +4 more
core  

Transplantation of older DCD livers in the machine perfusion era: a U.S. cohort study

Transplant International
Donation after circulatory death (DCD) livers increasingly use machine perfusion (MP). This study evaluates MP’s impact on older DCD livers based on data from the United Network for Data Sharing, covering all first adult DCD liver transplants (2016–2025).
Emmanouil Giorgakis, Ioannis A. Ziogas, Dimitrios Moris, Dimitrios N. Varvoglis, Charalampos Theocharopoulos, Dor Yoeli, Megan A. Adams, Andrew S. Barbas, Martin I. Montenovo, Melissa Chen, Sorabh Kapoor, Esteban Calderon, Andrew M. Moon, Sasha Deutch-Link, Hersh Shroff, Neil D. Shah, Oren K. Fix, A. Sidney Barritt, Amit K. Mathur, Trevor Nydam, Chirag S. Desai, Paulo N. Martins, Andrea Schlegel   +22 more
doaj   +1 more source

Letter to the editor: normothermic regional perfusion - a case worth defending

We read with interest the editorial by Rubin. We find his position about normothermic regional perfusion (NRP) in donation after cardiac death (DCD) to be problematic.
Gillian Crowe (19114867), James O'Rourke (10045943)   +1 more
core   +2 more sources

Ex-vivo normothermic liver perfusion: an update.

, 2010
PURPOSE OF REVIEW: There is increasing disparity between the supply of acceptable donor organs and the number of potential transplant recipients. The shortage of organs for transplantation demands optimal utilization of a wider spectrum of donor organs ...
Friend, PJ, Vogel, T, Friend, Peter, Brockmann, JG   +3 more
core   +1 more source

Clinical Utility and Evolution of Donor Serum Lactate During Normothermic Regional Perfusion in Uncontrolled Donation After Circulatory Death [PDF]

Kidney transplantation from uncontrolled donor after circulatory death (uDCD) showed a higher incidence of delayed graft function and primary failure. The aim of this study was to study basal and kinetic evolution of lactate values in uDCD preserved on ...
Roque, Rebeca, Paredes, David, Rodríguez, Camino, Sánchez-Etayo, Gerard, Reinoso, Johanna   +4 more
core   +1 more source