Results 61 to 70 of about 2,877,363 (151)

Perfusate Liver Arginase 1 Levels After End-Ischemic Machine Perfusion Are Associated with Early Allograft Dysfunction

Biomedicines
Background/Objectives: The rising use of liver grafts from donation after circulatory death (DCD) has been enabled by advances in normothermic regional perfusion (NRP) and machine perfusion (MP) technologies. We aimed to identify predictive biomarkers in
Giuseppina Basta, Serena Babboni, Daniele Pezzati, Serena Del Turco, Emanuele Balzano, Gabriele Catalano, Lara Russo, Giovanni Tincani, Paola Carrai, Stefania Petruccelli, Jessica Bronzoni, Caterina Martinelli, Simona Palladino, Arianna Trizzino, Lorenzo Petagna, Renato Romagnoli, Damiano Patrono, Giandomenico Biancofiore, Adriano Peris, Chiara Lazzeri, Davide Ghinolfi   +20 more
doaj   +1 more source

Pushing the Limit for Marginal Grafts in the Era of Machine Perfusion: A Tale of HOPE From a Leading Italian Institution

Artificial Organs, Volume 50, Issue 7, Page 1027-1036, July 2026.
HOPE has improved outcomes in ECD liver transplantation and allowed the safe utilization of increasingly marginal grafts with favorable results. ABSTRACT Background The advent of machine perfusion (MP) has significantly improved post‐liver transplantation (post‐LT) outcomes, potentially enabling the use of increasingly marginal grafts and expanding the
Gerti Dajti, Giuliana Germinario, Enrico Prosperi, Guido Fallani, Chiara Bonatti, Edoardo Prosperi, Antonio Siniscalchi, Maria Cristina Morelli, Antonietta D’ Errico, Matteo Serenari, Massimo Del Gaudio, Chiara Zanfi, Federica Odaldi, Lorenzo Maroni, Andrea Laurenzi, Matteo Cescon, Matteo Ravaioli   +16 more
wiley   +1 more source

Use of ex vivo normothermic machine perfusion after normothermic regional perfusion to salvage a poorly perfused DCD kidney.

, 2020
Normothermic regional perfusion (NRP) and normothermic machine perfusion (NMP) have both been used in the procurement and conditioning of abdominal organs from donation after circulatory death donors with reported improved outcomes for the recipients ...

core   +2 more sources

Normothermic Versus Hypothermic Cardiopulmonary Bypass in Children Undergoing Open Heart Surgery (Thermic-2): Study Protocol for a Randomized Controlled Trial

JMIR Research Protocols, 2015
BackgroundDuring open heart surgery, patients are connected to a heart-lung bypass machine that pumps blood around the body (“perfusion”) while the heart is stopped. Typically the blood is cooled during this procedure (“hypothermia”) and warmed to normal
Baos, Sarah, Sheehan, Karen, Culliford, Lucy, Pike, Katie, Ellis, Lucy, Parry, Andrew J, Stoica, Serban, Ghorbel, Mohamed T, Caputo, Massimo, Rogers, Chris A   +9 more
doaj   +1 more source

Magnetic Resonance Imaging Evaluation of Functional Differences Between In Vivo Human Kidneys and Discarded Human Kidneys During Ex Vivo Normothermic Machine Perfusion

Artificial Organs, Volume 50, Issue 7, Page 1037-1051, July 2026.
Comparative MRI of in vivo kidneys and ex vivo donor kidneys during NMP revealed marked physiological differences and limited correspondence with conventional perfusion or injury metrics. These distinct ex vivo MRI signatures emphasize the need to consider parameters beyond conventional in vivo functional markers when assessing organ viability during ...
Tim L. Hamelink, Chris L. Jaynes, L. Annick van Furth, Johannes Castelein, Nathan Ooms, Veerle A. Lantinga, Baran Ogurlu, Xiaopeng Zhou, Ulrike Dydak, Henri G. D. Leuvenink, Anna Krarup Keller, Ronald J. H. Borra, Cyril Moers   +12 more
wiley   +1 more source

Consensus Statement of the National Consortium on Normothermic Regional Perfusion for Organ Donation after Circulatory Determination of Death in India

Indian Journal of Transplantation
Background: India ranked third globally in organ transplants in 2023, yet over majority of its 18,378 transplants were from living donors, with deceased donor numbers remaining critically low.
Avish Sheth, Ravi Mohanka, Jumana Yusuf Haji, Kumud Dhital, Amay Banker, Ashish Sharma, Anil Kumar, Darius F. Mirza, Dhvani Mehta, Kalaimani Dhandapani, Milind P. Hote, Philip Thomas, Rahul Anil Pandit, Raj Kumar Mani, Sandeep Attawar, Sanjay P. Kolte, Shrikanth Shrinivasan, Subhash Gupta, Surendra Kumar Mathur, Venugopal Kota, Sunil Shroff   +20 more
doaj   +1 more source

Missed Opportunities in Donation After Circulatory Death Liver Transplantation: A National Analysis of Non‐Allocation and Non‐Procurement

Clinical Transplantation, Volume 40, Issue 6, June 2026.
ABSTRACT Introduction A significant percentage of livers from DCD donors do not undergo allocation or procurement. We identified non‐allocated and non‐procured livers to understand reasons for non‐utilization and to quantify allografts potentially suitable for transplantation.
Andrew D. Shubin, Shreya L. Hariharakumar, Lauren E. Matevish, Taylor M. Coe, Ratul Bhattacharrya, Jason Y. Wang, Brian A. Jafari, Chistine S. Hwang, Yanik J. Bababekov, Parsia A. Vagefi, Madhukar S. Patel   +10 more
wiley   +1 more source

Reply to: "Normothermic regional perfusion - What is the benefit?".

, 2019
Wethank Drs. Schlegel, Muiesan, and Dutkowski for their interest in our manuscript1 and are delighted to provide clearer and updated information regarding the use of normothermic regional perfusion (NRP) in controlled donation after circulatory death ...
Hessheimer, Amelia J, Ramirez, Pablo, Fundora-Suarez, Yiliam, Pardo, Fernando, Sanchez Turrion, Victor, Marin, Luis Miguel, Charco, Ramon, Gomez, Manuel, Gastaca, Mikel, Lopez-Baena, Jose Angel, Ruíz, Patricia, Parrilla, Pascual, Rodriguez, Juan Carlos, Pacheco, David, Llado, Laura, Rodríguez-Laiz, Gonzalo, Rivas, Jose Ignacio, Lopez-Andujar, Rafael, Villar, Jesus, Jimenez, Carlos, Coll, Elisabeth, Gomez-Bravo, Miguel Angel, Dominguez-Gil, Beatriz, Garcia-Valdecasas, Juan Carlos, Bosca, Andrea, Garcia-Sesma, Alvaro, Blanco, Gerardo, Santoyo, Julio, Sanchez, Belinda, Fondevila, Constantino, Lopez-Monclus, Javier, Briceño, Javier, Barrera, Manuel   +32 more
core   +1 more source

Contrast‐enhanced ultrasound and photoacoustic imaging to assess early and late renal ischemia‐reperfusion injuries in male mice

Physiological Reports, Volume 14, Issue 12, June 2026.
Abstract Tissue perfusion and oxygenation, key factors of renal ischemia‐reperfusion injury (RIR), can be assessed using contrast‐enhanced ultrasound (CEUS) and photoacoustic (PA) imaging. We hypothesized that early changes in renal perfusion and oxygenation caused by IRI, or protection by mild therapeutic hypothermia (mTH), could be detected and ...
Maxime Schleef, Corentin Tournebize, Christelle Leon, Bruno Pillot, Stéphanie Chanon, Gabriel Bidaux, Laurent Juillard, Fitsum Guebre‐Egziabher, Delphine Baetz, Sandrine Lemoine   +9 more
wiley   +1 more source

Donor and recipient risk factors for the development of primary graft dysfunction following lung transplantation

Frontiers in Immunology
Primary Graft Dysfunction (PGD) is a major cause of both short-term and long-term morbidity and mortality following lung transplantation. Various donor, recipient, and technical risk factors have been previously identified as being associated with the ...
J. Asher Jenkins, Ricardo Verdiner, Ashraf Omar, Juan Maria Farina, Renita Wilson, Jonathan D’Cunha, Pedro Augusto Reck Dos Santos   +6 more
doaj   +1 more source