Results 51 to 60 of about 2,877,363 (151)

Regional hypothermia improves gastric microcirculatory oxygenation during hemorrhage in dogs.

PLoS ONE, 2019
Mild systemic hypothermia increases gastric mucosal oxygenation (μHbO2) during hemorrhagic shock in dogs. In the context of critical blood loss hypothermia might be fatal due to adverse side effects.
Richard Truse, Michael Smyk, Jan Schulz, Anna Herminghaus, Andreas P M Weber, Tabea Mettler-Altmann, Inge Bauer, Olaf Picker, Christian Vollmer   +8 more
doaj   +1 more source

Passive hyperthermia increases blood circulation in specific regions, largely independent of conduit artery mechanics and cardiac performance

Experimental Physiology, EarlyView.
Abstract Passive hyperthermia increases net peripheral and systemic blood flow in humans and other animals, yet the underlying haemodynamic forces that selectively accelerate blood movement remain incompletely characterized. Wave intensity analysis offers insight into the respective contributions of the heart and the vascular system to changes in blood
Nuno Koch Esteves, Kazuhito Watanabe, Francesca R. Cavallo, Ashraf W. Khir, José González‐Alonso   +4 more
wiley   +1 more source

Viability Criteria during Liver Ex-Situ Normothermic and Hypothermic Perfusion [PDF]

, 2022
With the increased use of extended-criteria donors, machine perfusion became a beneficial alternative to cold storage in preservation strategy for donor livers with the intent to expand donor pool. Both normothermic and hypothermic approach achieved good
Riccardo De Carlis, De Carlis, Riccardo, Torri, Francesco, Melandro, Fabio, De Simone, Paolo, De Carlis, Luciano, Andrea Lauterio, Davide Ghinolfi, Ghinolfi, Davide, Francesco Torri, Paolo De Simone, Fabio Melandro, Lauterio, Andrea, Luciano De Carlis   +13 more
core   +1 more source

Lung recovery utilizing thoracoabdominal normothermic regional perfusion during donation after circulatory death: The Colorado experienceCentral MessagePerspective

JTCVS Techniques, 2023
Objective: Donation after circulatory death (DCD) procurement and transplantation after thoracoabdominal normothermic regional perfusion (TA-NRP) remains a novel technique to improve cardiac and hepatic allograft preservation but may be complicated by ...
Michael T. Cain, MD, Sarah Y. Park, MD, Michal Schäfer, MD, PhD, Emily Hay-Arthur, BA, George A. Justison, CCP, Qui Peng Zhan, MD, PhD, David Campbell, MD, John D. Mitchell, MD, Simran K. Randhawa, MD, Robert A. Meguid, MD, Elizabeth A. David, MD, T. Brett Reece, MD, MBA, Joseph C. Cleveland, Jr, MD, Jordan R.H. Hoffman, MD, MPH   +13 more
doaj   +1 more source

Brain strain: Blood flow and metabolism in environmental extremes

Experimental Physiology, EarlyView.
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak, Damian M. Bailey, Travis D. Gibbons, Philip N. Ainslie   +3 more
wiley   +1 more source

When Machine Perfusion Falls Short: Identifying Risks of Liver Graft Failure After Normothermic Machine Perfusion

Artificial Organs, Volume 50, Issue 10, Page 1407-1417, October 2026.
Analysis of 4928 normothermic machine perfusion liver transplants reveals that recipient factors, particularly MELD ≥ 35, surgical complexity, ICU status, and functional impairment are stronger predictors of graft failure than donor characteristics, emphasizing the continued importance of clinical judgment in patient selection.
Lauren E. Matevish, Abdullah K. Malik, Milana Harris, Ahmad Anouti, Taylor M. Coe, Simon Moosburner, Nathanael Raschzok, Arjmand Mufti, Parsia A. Vagefi, Madhukar S. Patel   +9 more
wiley   +1 more source

Revolutionizing Donor Heart Procurement: Innovations and Future Directions for Enhanced Transplantation Outcomes

Journal of Cardiovascular Development and Disease
Heart failure persists as a critical public health challenge, with heart transplantation esteemed as the optimal treatment for patients with end-stage heart failure.
Marc Leon
doaj   +1 more source

Comparing Early Graft Dysfunction Scores in Liver Transplantation After Ex‐Situ Normothermic Machine Perfusion

Clinical Transplantation, Volume 40, Issue 8, August 2026.
ABSTRACT Introduction As normothermic machine perfusion (NMP) maintains liver grafts in a near‐physiologic state, uncoupling ischemia–reperfusion injury from the recipient, the validity of early graft dysfunction scores from the static cold storage (SCS) era are uncertain.
Kejal Shah, Sydney Castellanos, April J. Logan, Leonid Gorelik, Annelise Nolan, Manoj Iyer, Lauren Von Stein, Wei Chen, Ayato Obana, Ashley Limkemann, Navdeep Singh, Sylvester Black, William K. Washburn, Austin D. Schenk, Musab Alebrahim, Sai Rithin Punjala   +15 more
wiley   +1 more source

Hypothermic Machine Perfusion in Deceased Donor Kidney Transplantation: Provider and Transplant Center Practices and Perspectives

Clinical Transplantation, Volume 40, Issue 8, August 2026.
ABSTRACT Background Hypothermic machine perfusion (HMP), an organ preservation technique used in deceased donor kidney transplantation, improves early outcomes compared to traditional static cold storage while also providing a loosely validated organ viability assessment. Methods We designed a survey to better understand the practices, perceptions, and
Beatrice P. Concepcion, Laura A. Binari, Vasanthi Balaraman, Angie Nishio‐Lucar, Anju Yadav, Ankita Patel, Kenneth J. Woodside, Krista L. Lentine, M. Lee Sanders, Oluwafisayo O. Adebiyi, Sabiha M. Hussain, Shikha Mehta, Vignesh Viswanathan, Xingxing S. Cheng, Ronald F. Parsons   +14 more
wiley   +1 more source

Willing to Donate? A Quantitative and Thematic Analysis of Attitudes to Deceased Organ Donation in Different Circumstances

Health Expectations, Volume 29, Issue 4, August 2026.
ABSTRACT Introduction The UK public's willingness to donate, knowledge of, and concerns about different organ donation scenarios are not known. Methods A validated questionnaire was developed based on a literature review of the ethical issues associated with uncontrolled Donation after Circulatory Death (uDCD).
Weiyi Tan, Janet Cruse, Dominic Summers, Zoë Fritz   +3 more
wiley   +1 more source