Results 41 to 50 of about 2,877,363 (151)

Heart Donation After Controlled Circulatory Death in Noncardiac Surgery Hospitals With a Mobile Heart Team: A Case Series From an Italian Regional Program and Integrated Review of the Literature

Artificial Organs, EarlyView.
In this series of 19 DCD donors using TA‐NRP, 89.5% of hearts were successfully transplanted with no PGD, no postoperative ECMO, and no 30‐day mortality, demonstrating the feasibility and safety of this approach. ABSTRACT Controlled donation after circulatory death (cDCD) with thoracoabdominal normothermic regional perfusion (TA‐NRP) has emerged ...
Maria Benedetto, Valentina Roncarati, Arianna Campana, Erika Cordella, Domenico Nocera, Sofia Martin‐Suarez, Luca Botta, Davide Pacini, Letizia Perinati, Massimo Baiocchi, Tommaso Tonetti, Fabrizio Monaco   +11 more
wiley   +1 more source

Normothermic regional perfusion does not hasten death [PDF]

A novel method of organ donation after circulatory death called normothermic regional perfusion (NRP) could mitigate the organ shortage crisis and lead to superior outcomes for organ recipients.
Lee, Harrison
core   +3 more sources

Surgical technique of donation after circulatory death heart procurement using direct procurement and hypothermic oxygenated perfusion preservation

JHLT Open
Introduction: Donation after circulatory death (DCD) has re-emerged as a means of expanding the donor heart pool. Current clinical practice relies mainly on direct procurement followed by normothermic machine perfusion or on thoraco-abdominal ...
K. Vandendriessche, J. Brouckaert, K. Van de Voorde, F. Gaublomme, K. Degezelle, J. Van Cleemput, A. Wallinder, F. Rega   +7 more
doaj   +1 more source

Death Determination, the Dying Process and the Dead Donor Rule: A Critical Analysis of the Italian 20‐Minute No‐Touch Period in Controlled Donation After Circulatory Determination of Death

Bioethics, EarlyView.
ABSTRACT In Italy, controlled Donation after Circulatory Determination of Death (cDCDD) requires a 20‐min no‐touch period documented by continuous electrocardiographic monitoring. Since Italian law adopts a single brain‐based definition of death, this procedure serves as an indirect determination of the irreversible cessation of all brain functions ...
Lucia Craxì
wiley   +1 more source

Differential intestinal injury and unchanged systemic inflammatory responses to leg and whole‐body passive hyperthermia in healthy humans

Experimental Physiology, EarlyView.
Abstract Hyperthermia can cause intestinal injury, facilitating endotoxin translocation and an inflammatory response that has been associated with heat illness. However, the potential occurrence of these responses has been incompletely reported during passive hyperthermia, and the independent effect of hyperthermia is equivocal.
Oliver R. Gibson, Orlando Laitano, Kazuhito Watanabe, José González‐Alonso   +3 more
wiley   +1 more source

The Evolving Role of Extracorporeal In Situ Perfusion Technology in Organ Donor Recovery with Donation After Circulatory Determination of Death Organ Donors

Medicina
The need for organs suitable for transplantation has continued to rise as need outweighs availability. Increased demand has driven innovation in the field.
Victoria R. Hammond, Marisa E. Franklin, Glen A. Franklin   +2 more
doaj   +1 more source

Increases in skin perfusion and blood oxygen in the non‐exercising human limbs during exercise in the heat: Implications for control of circulation

Experimental Physiology, EarlyView.
Abstract Blood flow in the inactive limb tissues and skin is widely thought to decline during incremental exercise to exhaustion due to augmented sympathoadrenal vasoconstrictor activity, but direct evidence to support this view is lacking. Here, we investigated the inactive‐forearm haemodynamic (Q̇forearm${\dot{Q}}_{\mathrm{forearm}}$) and oxygenation
Steven J. Trangmar, José González‐Alonso   +1 more
wiley   +1 more source

Extracorporeal normothermic pancreas perfusion [PDF]

, 2016
Pancreas and islet transplantation are important treatment options for insulin dependent diabetes. However, one of the main challenges in pancreas and islet transplantation lies in organ (pancreas) preservation.
Kuan, Kean Guan
core   +1 more source

Cerebrovascular regulation during heat stress

Experimental Physiology, EarlyView.
Abstract Given that the brain is a highly metabolic organ and is enclosed by the skull, effective regulation of cerebral blood flow (CBF), not only for oxygen and nutrients supply but also as a means of convective heat exchange, is critical for preventing excessive elevations in brain temperature.
Kanoko Ito, Manabu Shibasaki
wiley   +1 more source

Outcome reporting for liver transplantation machine perfusion studies: a systematic reviewResearch in context

EClinicalMedicine
Summary: Background: Studies examining machine perfusion (MP) in liver transplantation (LT) report variable post-transplant outcomes, making comparison difficult.
Sangeeta Satish, Ayesha A. Qureshi, Fariba Abbassi, Muhammad A. Nadeem, Tobias Diwan, Laura Batista De Oliveira, Charles Miller, Koji Hashimoto, Chase J. Wehrle, Pierre-Alain Clavien, Andrea Schlegel   +10 more
doaj   +1 more source