Results 31 to 40 of about 2,877,363 (151)

Contemporary considerations in solid organ transplantation utilizing DCD donors

Transplantation Reports, 2022
Introduction: Donation after cardiac death (DCD) has been leading the way to help bridge the growing gap between availability of donors and recipients on waitlist.
Farjad Siddiqui, Yazan Al-Adwan, Jayanthan Subramanian, Mitchell L. Henry   +3 more
doaj   +1 more source

The role of sequential normothermic regional perfusion and end-ischemic normothermic machine perfusion in liver transplantation from very extended uncontrolled donation after cardiocirculatory death

, 2022
The use of pre-procurement normothermic regional perfusion (NRP) allowed us to implement controlled DCD liver transplantation with results comparable to brain death donors, but the use of uncontrolled DCD is declining due to logistic challenges and the ...
Bindi, Maria, Torri, Francesco, Del Turco, Serena, Melandro, Fabio, Esposito, Massimo, Biancofiore, Giandomenico, Lazzeri, Chiara, De Simone, Paolo, Peris, Adriano, Maria Isabella Rotondo, Ghinolfi, Davide, Basta, Giuseppina, Davide Ghinolfi, Francesco Torri, Rotondo, Maria Isabella, Chiara Lazzeri, Serena Del Turco, Paolo De Simone, Giuseppina Basta, Massimo Esposito, Fabio Melandro, Giandomenico Biancofiore, Adriano Peris, Maria Bindi   +23 more
core   +1 more source

Machine perfusion for liver transplantation: opportunities and challenges for the next generation of transplant surgeons

Frontiers in Transplantation
Machine perfusion is reshaping liver transplantation by turning preservation from passive storage into an active, physiologic intervention. This review synthesizes randomized and real-world evidence on hypothermic oxygenated and normothermic approaches ...
Cody L. Mullens, Cody L. Mullens, Cody L. Mullens, Kumaran Shanmugarajah, Glenn K. Wakam   +4 more
doaj   +1 more source

Texture Analysis Using Indocyanine Green Fluorescence Measurement During Porcine Hypothermic Oxygenated Machine Perfusion

Artificial Organs, EarlyView.
A novel quantitative method using Indocyanine Green (ICG) fluorescence image for assessing organ viability during hypothermic oxygenated machine perfusion (HOPE), specifically focusing on homogeneous flow distribution analyzed with the gray‐scale level co‐occurrence matrix (GLCM) method, can predict portal vein resistance induced by ischemic ...
Yuga Okazawa, Hiromichi Obara, Taiki Mori, Satoshi Muto, Mio Takashima, Masafumi Furukawa, Hiroki Kaneko, Tetsuya Nakajo, Shohei Ishizawa, Seisuke Sakamoto, Naoto Matsuno   +10 more
wiley   +1 more source

Strategies for Expanding Donors Pool in Heart Transplantation

Reviews in Cardiovascular Medicine, 2022
Heart transplant remains the criterion standard treatment for patients in end-stage heart failure. Improvement in the post-heart transplant outcomes in the last decade has contributed to increased demand for organs.
Samuel Jacob, Pankaj Garg, Ishaq Wadiwala, John H. Yazji, Mohammad. Alomari, Emad Alamouti-fard, Md Walid Akram Hussain, Si M. Pham   +7 more
doaj   +1 more source

Monitoring Mitochondrial Function With High‐Resolution Respirometry During Ex‐Situ Heart Perfusion

Artificial Organs, EarlyView.
Normothermic ESHP preserves mitochondrial respiratory function over 6 h in a porcine model (n = 6): OXPHOS capacities across NADH‐, fatty‐acid‐, and succinate‐linked pathways remain stable, with reduced cytochrome‐c control efficiency indicating improved outer‐membrane integrity. HRR provides a rapid, actionable readout for organ assessment.
Lukas Stastny, Julia Hofmann, Andras T. Meszaros, Alexandra Ampferer, Gabriel Putzer, Nina Perkins, Natalie Huemer, Florian Sommerauer, Judith Martini, Julian Wagner, Michael Grimm, Stefan Schneeberger, Julia Dumfarth   +12 more
wiley   +1 more source

Sequential use of normothermic regional and ex-situ machine perfusion in DCD liver transplant [PDF]

, 2020
In Italy, 20 minutes of continuous, flat-line electrocardiogram are required for declaration of death. In the setting of organ donation after cardiocirculatory death (DCD), prolonged warm ischemia time prompted introduction of abdominal normothermic ...
Zanella, Alberto, Biancofiore, Giandomenico, De Simone, Paolo, Alberto Zanella, Peris, Adriano, Rossi, Giorgio, Ghinolfi, Davide, Marco Maggioni, Caterina Lonati, Paolo De Simone, Daniele Pezzati, Alessia Kersik, Maggioni, Marco, Erion Rreka, Kersik, Alessia, Daniele Dondossola, Lonati, Caterina, Lazzeri, Chiara, Reggiani, Paolo, Giorgio Rossi, Davide Ghinolfi, Riccardo Morganti, Cacciatoinsilla, Andrea, Chiara Lazzeri, Morganti, Riccardo, Paolo Reggiani, Giandomenico Biancofiore, Adriano Peris, Dondossola, Daniele, Andrea Cacciatoinsilla, Pezzati, Daniele, Rreka, Erion   +31 more
core   +1 more source

Successful heart transplantation from donation after euthanasia with distant procurement using normothermic regional perfusion and cold storage [PDF]

, 2022
While euthanasia has been legalized in a growing number of countries, organ donation after euthanasia is only performed in Belgium, the Netherlands, Spain, and Canada.
Hans, Gregory, Lievens, Isabelle, Lagny, Marc Gilbert, Rega, Filip, Ancion, Arnaud, Ledoux, Didier, Trung, Mai-Linh Nguyen, Defraigne, Jean Olivier, DEFRAIGNE, Jean, Brouckaert, Janne, De Troy, Erwin, Tchana-Sato, Vincent, Delbouille, Marie-Helene, Van Cleemput, Johan, Detry, Olivier, Rex, Steffen, Van den Eynde, Raf, Jaquet, Oceane   +17 more
core   +1 more source

Risk factors of delayed kidney graft function following donation after circulatory death – a retrospective cohort study of Swiss kidney transplants

Swiss Medical Weekly
AIMS OF THE STUDY: On 1 September 2011, donation after circulatory death (DCD) organ donation resumed in Switzerland after the DCD programme had been suspended for four years due to jurisdictional and medico-ethical discrepancies.
Maurice Bischof, Simon Schwab, Julius Weiss, Franziska Beyeler, Christian Brunner, Sabine Camenisch, Raphaël Giraud, Yvonne Hilpertshauser, Matthias Peter Hilty, Marco Rusca, Kai Tisljar, Thomas Müller, Franz Immer   +12 more
doaj   +1 more source

Impact of normothermic regional perfusion during DCD recovery on lung allograft function: A preclinical study

JHLT Open, 2023
Background: Normothermic regional perfusion (NRP) has been growing as a novel procurement strategy after circulatory death (donation after circulatory death (DCD)) in the context of heart transplantation.
Rafaela V.P. Ribeiro, MD, PhD, Frank A. Reynolds, CCP, Tiffany L. Sarrafian, DVM, PhD, Cristiano Spadaccio, MD, PhD, Clint Colby, CCP, Adam Richman, CCP, Jennifer L. Brazzell, DVM, MVetSc, Defne Gunes Ergi, MD, Salah Altarabsheh, MD, Benjamin T. Daxon, MD, Marcelo Cypel, MD, MSc, Sahar A. Saddoughi, MD, PhD   +11 more
doaj   +1 more source