Results 71 to 80 of about 2,877,363 (151)

The Top Five Advances in Solid Organ Transplantation in the Past Fifty Years

World Journal of Surgery, Volume 50, Issue 8, Page 2121-2124, August 2026.
Stephen J. Wigmore, Diana A. Wu
wiley   +1 more source

Patient perspectives on the ethics and acceptability of perfusion techniques for organ transplantation: a qualitative study

Transplant International
Perfusion technologies preserve and/or improve organ viability by restoring circulation to donor organs either outside the body (machine perfusion, MP) or inside the body of the deceased donor (normothermic regional perfusion, NRP).
Jaden Blazier, Jaden Blazier, Jaden Blazier, Eline M. Bunnik, Valerie Kortekaas, Esther W. de Bekker-Grob, Maartje H. N. Schermer, Niels van der Kaaij, Robert Minnee, Olivier Manintveld, Jeroen De Jonge, Emma K. Massey   +11 more
doaj   +1 more source

Commentator Discussion: Safe and controlled technique of aortic cannulation for thoracoabdominal normothermic regional perfusion [PDF]

JTCVS Techniques
doaj   +2 more sources

Regulated cell death and DAMPs as biomarkers and therapeutic targets in normothermic perfusion of transplant organs. Part 1: their emergence from injuries to the donor organ

Frontiers in Transplantation
This Part 1 of a bipartite review commences with a succinct exposition of innate alloimmunity in light of the danger/injury hypothesis in Immunology. The model posits that an alloimmune response, along with the presentation of alloantigens, is driven by ...
Walter G. Land, Walter G. Land, Walter G. Land, Andreas Linkermann, Andreas Linkermann, Andreas Linkermann   +5 more
doaj   +1 more source

Molecular and cellular adaptations to extended hypothermic oxygenated perfusion in donation-after-circulatory-death hearts in a porcine model

Frontiers in Cardiovascular Medicine
IntroductionDonation after circulatory death (DCD) criteria serves as a potential strategy to expand the organ pool for heart transplantation. However, DCD procurement introduces prolonged warm ischemic times that accelerate endothelial and cardiomyocyte
Morgan K. Moroi, Yaagnik Kosuri, Cary Karcher, Diana Albino, Diana Albino, Anthony Campbell, Arianna Adamo, Arianna Adamo, Emre Bektik, Christine Chan, Kenmond Fung, Miroslav Sekulic, Shaheer K. Faruqi, Shaheer K. Faruqi, Craig J. Goergen, Craig J. Goergen, Melissa Tamimi, Koji Takeda, Giovanni Ferrari   +18 more
doaj   +1 more source

Combined Hypothermic and Normothermic Machine Perfusion Improves Functional Recovery of Extended Criteria Donor Livers [PDF]

, 2018
Hypothermic oxygenated perfusion (HOPE) and normothermic perfusion are seen as distinct techniques of ex situ machine perfusion of the liver. We aimed to demonstrate the feasibility of combining both techniques and whether it would improve functional ...
Darius F. Mirza, Afford, Simon C, Wallace, Lorraine, Hynek Mergental, Mirza, Darius F, Andrea Schlegel, Attard, Joseph, Laing, Richard W, Joseph Attard, Richard W. Laing, M. Thamara P. R. Perera, Simon C. Afford, Bhogal, Ricky H, Desley A. H. Neil, Smith, Amanda, Yuri L. Boteon, Stefan Hübscher, Neil, Desley A H, Hübscher, Stefan, Ricky H. Bhogal, Boteon, Yuri L, Perera, M Thamara P R, Mergental, Hynek, Amanda Smith, Schlegel, Andrea, Lorraine Wallace   +25 more
core   +1 more source

Impact of the Composite Allocation Score on Lung Transplant Waitlist and Posttransplant Outcomes

Transplantation Direct
Background. On March 9, 2023, the Composite Allocation Score (CAS) was introduced for all lung transplantation (LT) candidates. We analyzed waitlist and posttransplant outcomes after CAS implementation. Methods. Using the United Network for Organ Sharing
Ye In Christopher Kwon, BA, Holly Caboti-Jones, BS, Michael Keller, BS, Andrew Min-Gi Park, BA, Alan Lai, BS, Rachit D. Shah, MD, Zachary Fitch, MD, Vigneshwar Kasirajan, MD, Vipul Patel, MD, Zubair A. Hashmi, MD   +9 more
doaj   +1 more source

Thoracoabdominal Normothermic Regional Perfusion Using Mobile Closed Extracorporeal Circuit in Circulatory Death Determination Heart Donors

Thoracoabdominal normothermic regional perfusion (TA-NRP) is increasingly implemented in donation after circulatory determination of death (DCD). Thoracoabdominal normothermic regional perfusion allows thoracic and abdominal organs to be perfused with ...
Zani G., Pacini D., Martin-Suarez Sofia., Antonini M. V., Circelli A., Botta L., Agnoletti V., Cordella E., Terzitta M. T.   +8 more
core   +1 more source

The perfused liver utilisation study (PLUS): challenges and innovation in the evaluation of an emerging technology

Transplant International
Previous studies suggest that donor liver normothermic machine perfusion (NMP) reduces injury and enables functional assessment, resulting in an increase in utilisation.
Simon Robert Knight, Helen L. Thomas, Rosemary Brown, Charlie Brown, Kerrie Brusby, Emily Arbon, Laura Silsby, Alice Newton, Jennifer Mehew, Aleema Iqbal, Katie Keen, Syeda Bahar, Christopher Watson, Brian Davidson, Brian Davidson, David Nasralla, Carlo Ceresa, Barbara Fiore, Ahmed E. Sherif, Colin Wilson, Balaji Mahendran, Joerg-Matthias Pollok, Joerg-Matthias Pollok, Rebeca S. Mateos, Wayel Jassem, Rohit Gaurav, Gabriel C. Oniscu, Craig Marshall, Angus Hann, Reena Ravikumar, Constantin Coussios, Peter J. Friend   +31 more
doaj   +1 more source

Regulated cell death and DAMPs as biomarkers and therapeutic targets in normothermic perfusion of transplant organs. Part 2: implementation strategies

Frontiers in Transplantation
This Part 2 of a bipartite review commences with the delineation of a conceptual model outlining the fundamental role of injury-induced regulated cell death (RCD) in the release of DAMPs that drive innate immune responses involved in early inflammation ...
Walter G. Land, Walter G. Land, Walter G. Land, Andreas Linkermann, Andreas Linkermann, Andreas Linkermann   +5 more
doaj   +1 more source