Results 21 to 30 of about 16,047 (285)
Antiviral Activity of Olanexidine-Containing Hand Rub against Human Noroviruses
mBio, 2022 Human noroviruses (HuNoVs) are highly contagious and cause nonbacterial acute gastroenteritis in all age groups worldwide. Since the introduction of rotavirus vaccines, HuNoVs have become the leading cause of diarrheal illness in children. ABSTRACT Human
Khalil Ettayebi +7 more
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The Dual Tropism of Noroviruses [PDF]
Journal of Virology, 2018 Noroviruses are highly prevalent enteric RNA viruses. Human noroviruses (HuNoVs) cause significant morbidity, mortality, and economic losses worldwide.
Christiane E. Wobus
openalex +3 more sources
Are Noroviruses Emerging? [PDF]
Emerging Infectious Diseases, 2005 In 1972, noroviruses (previously called "Norwalk-like viruses") were discovered as the first viruses definitively associated with acute gastroenteritis. During the next 2 decades, researchers were unable to develop simple methods to detect these common viruses or to find the etiologic agents of nonbacterial gastroenteritis outbreaks and ...
Marc‐Alain Widdowson +2 more
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Noroviruses—The State of the Art, Nearly Fifty Years after Their Initial Discovery
Viruses, 2021 Human noroviruses are recognised as the major global cause of viral gastroenteritis. Here, we provide an overview of notable advances in norovirus research and provide a short recap of the novel model systems to which much of the recent progress is owed.
Louisa F. Ludwig-Begall +2 more
semanticscholar +1 more source
Evolutionary analyses of emerging GII.2[P16] and GII.4 Sydney [P16] noroviruses
Virus Evolution, 2022 GII.2[P16] and GII.4 Sydney [P16] are currently the two predominant norovirus genotypes. This study sought to clarify their evolutionary patterns by analyzing the major capsid VP1 and RNA-dependent RNA polymerase (RdRp) genes.
G. Zheng +3 more
semanticscholar +1 more source
PLoS Pathogens, 2021 Norovirus is a major cause of acute gastroenteritis worldwide. Over 30 different genotypes, mostly from genogroup I (GI) and II (GII), have been shown to infect humans.
K. Tohma +16 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance The GII.4 genotype of human noroviruses accounts for the majority of gastroenteritis outbreaks worldwide. This predominance is characterized by the chronological emergence of new variants in response to immune pressure.
J. Kendra +4 more
semanticscholar +1 more source
bioRxiv, 2021 The cGAS-STING pathway is central to the IFN response against DNA viruses. However, recent studies are increasingly demonstrating its role in the restriction of some RNA viruses.
A. Jahun +7 more
semanticscholar +1 more source
Broadly cross-reactive human antibodies that inhibit genogroup I and II noroviruses
Nature Communications, 2021 The rational development of norovirus vaccine candidates requires a deep understanding of the antigenic diversity and mechanisms of neutralization of the virus. Here, we isolate and characterize a panel of broadly cross-reactive naturally occurring human
Gabriela Alvarado +7 more
semanticscholar +1 more source
Autophagy and Noroviruses [PDF]
Viruses, 2019 Autophagy is an essential cellular process by which a cell degrades materials within its cytoplasm. Intracellular pathogens like viruses must deal with autophagy, either positively or negatively, for their own survival and replication. For some viruses, autophagy can even play proviral roles, helping their replication or dissemination.
Kevin Furlong, Seungmin Hwang
openaire +3 more sources