Results 121 to 130 of about 1,748,176 (291)

The 14 month wind stressed residual circulation (pole tide) in the North Sea [PDF]

open access: yes
From published research it is known that a quasi-periodic 14 month atmospheric pressure oscillation of a few tenths of a millibar exists in the region of the North and Baltic Seas.
Oconnor, W. P.
core   +1 more source

PICES Press, Vol. 8, No. 2, July 2000 [PDF]

open access: yes, 2000
Beyond El Nino Conference The status of the Bering Sea: June - December, 1999 The state of the western North Pacific in the second half of 1999 The state of the eastern North Pacific since autumn 1999 Project Argo Report of the ICES Zooplankton

core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

North Sea oil and genuine saving in the Scottish economy [PDF]

open access: yes, 2011
The World Bank has published estimates of sustainability of consumption paths by adjusting saving rates to take account of the depletion of non-renewable resources.
Bremner, Greg, Cross, Rod
core   +4 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Nd & Hf concentrations and isotopic compositions in the Baltic Sea [PDF]

open access: yes, 2012
Within a process study in the framework of the international GEOTRACES program and led by the Institute of Oceanology of the Polish Academy of Sciences (IOPAN) a two-week cruise on the R/V Oceania sailed in November 2011 to investigate the distribution ...
Chen, Tianyu   +2 more
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Effects of Increased Calcium, Magnesium, and Potassium Ion Concentrations on Survival Conditions, Growth Performance, and Physiological Parameters in Sea Urchin (Strongylocentrotus intermedius)

open access: yesBiology
This study examined the effects of calcium, magnesium, and potassium ion concentrations on Strongylocentrotus intermedius through seven experimental rearing groups: two calcium ion levels (550 mg/L and 733 mg/L), two magnesium ion levels (1727 mg/L and ...
Xuechun Jiang   +9 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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