Results 111 to 120 of about 20,291 (261)

An unusual case of multiple myeloma [PDF]

, 2013
The case concerns the unusual presentation of a non-secretory multiple myeloma with diarrhoea secondary to large bowel infiltration. In December 2009, a 74-year-old lady presented to hospital and complained of a two year history of intermittent ...
Delicata, Julian, Farrugia, Daniel
core  

Unveiling the Demographics and Clinical Characteristics of Diabetic Neuropathy: Findings From the National Health Insurance Service, 2012–2017

Journal of Diabetes, Volume 18, Issue 5, May 2026.
Diabetic neuropathy prevalence declined from 23.4% to 21.5% between 2012 and 2017. About half received treatment, mainly α‐lipoic acid monotherapy; patients were older with comorbidities, leading to more hospitalizations. ABSTRACT Background Diabetic neuropathy (DN) is the most common chronic complication of Type 2 diabetes mellitus (T2DM), with ...
Su Jin Jeong, Sun Keun Kim, Chong Hwa Kim   +2 more
wiley   +1 more source

Pattern of c-Fos expression induced by tail suspension test in the mouse brain

Heliyon, 2017
The tail suspension test (TST) has been widely used as a screening assay for antidepressant drugs. However, the neural substrates underlying the stress response and antidepressant-like effect during the TST remain largely unknown despite the prevalence ...
Kentaro Hiraoka, Keisuke Motomura, Satoru Yanagida, Ayako Ohashi, Nozomi Ishisaka-Furuno, Shigenobu Kanba   +5 more
doaj   +1 more source

Pregabalin efficacy in painful diabetic peripheral neuropathy: A focused analysis of optimal dosing and the relationship of baseline glycemic control

Journal of Diabetes Investigation, Volume 17, Issue 5, Page 827-834, May 2026.
ABSTRACT Introduction Diabetic neuropathy, the most common long‐term complication of diabetes, frequently presents as painful diabetic peripheral neuropathy (pDPN), significantly impairing patients' quality of life. Pregabalin is an established treatment for pDPN, but optimal dosing and the influence of glycemic control on efficacy remain uncertain ...
Ashish Bajaj, Gordon Sloan, Chris Walker, Egbert Biesheuvel, Sagar Suresh Kumbhar, Gavin Lyndon, Solomon Tesfaye   +6 more
wiley   +1 more source

The limited utility of electrocardiography variables used to predict arrhythmia in psychotropic drug overdose [PDF]

, 2003
The aim of the present study was to examine the relationship between serious arrhythmias in patients with psychotropic drug overdose and electrocardiography (ECG) findings that have been suggested previously to predict this complication.Thirty-nine ...
Buckley, Nicholas A., Chevalier, Stephen, Leditschke, I. Anne, O'Connell, Dianne L., Leitch, James, Pond, Susan M.   +5 more
core   +1 more source

Suicidal ideation during treatment of depression with escitalopram and nortriptyline in Genome-Based Therapeutic Drugs for Depression (GENDEP): a clinical trial

BMC Medicine, 2009
Background Suicidal thoughts and behaviours during antidepressant treatment, especially during the first weeks of treatment, have prompted warnings by regulatory bodies.
Giovannini Caterina, Zobel Astrid, Strohmaier Jana, Jorgensen Lisbeth, Szczepankiewicz Aleksandra, Placentino Anna, Souery Daniel, Maier Wolfgang, Hauser Joanna, Henigsberg Neven, Mors Ole, Rietschel Marcella, Marusic Andrej, Uher Rudolf, Perroud Nader, Elkin Amanda, Gunasinghe Cerisse, Gray Joanna, Campbell Desmond, Gupta Bhanu, Farmer Anne E, McGuffin Peter, Aitchison Katherine J   +22 more
doaj   +1 more source

Antibacterial Evaluation of Tricyclic Antidepressants Against S. aureus and the Possible Pathways of the Mechanism of Action

Pathogens
The resistance of Staphylococcus aureus to conventional pharmacological treatments has gradually increased. Thus, new therapeutic strategies are needed.
Vitória Pessoa de Farias Cabral, Daniel Sampaio Rodrigues, Lívia Gurgel do Amaral Valente Sá, Lara Elloyse Almeida Moreira, Cecília Rocha da Silva, João Batista de Andrade Neto, Érica Rayanne Mota da Costa, Thais Lima Ferreira, Leilson Carvalho de Oliveira, Beatriz Oliveira de Souza, Dávylla Rênnia Saldanha Pinheiro, Bruno Coêlho Cavalcanti, Islay Lima Magalhães, Manoel Odorico de Moraes, Hélio Vitoriano Nobre Júnior   +14 more
doaj   +1 more source

Use of combinatorial pharmacogenomic testing in two cases from community psychiatry

Pharmacogenomics and Personalized Medicine, 2016
Eve S Fields,1 Raymond A Lorenz,2 Joel G Winner2 1Northwest Center for Community Mental Health, Reston, VA, USA; 2Assurex Health, Mason, OH, USA Abstract: This report describes two cases in which pharmacogenomic testing was utilized to guide medication ...
Fields ES, Lorenz RA, Winner JG
doaj  

A review of interventions for smoking cessation

Sri Lanka Journal of Psychiatry, 2017
BackgroundDiverse interventions for cessation of smoking, pharmacological and otherwise, have been studied, with less attention being paid to unassisted cessation.
M. Rajasuriya
doaj   +1 more source

Evaluation of the Efficacy and Safety of the Fixed-Dose Combination of Nortriptyline-Pregabalin Versus Duloxetine-Pregabalin in the Treatment of Painful Diabetic Peripheral Neuropathy in a Tertiary Care Center in North India

Journal of Diabetology
Introduction: About 25% of patients with diabetes mellitus have painful diabetic peripheral neuropathy (PDPN). Chronic hyperglycemia causes neuronal death and nerve regeneration inhibition, causing diabetic neuropathy.
Husain Abbas, Mujahid Beg, Hamid Ashraf, Syed Hasan Amir, Akash Priyadrashi   +4 more
doaj   +1 more source