Results 111 to 120 of about 94,967 (299)

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Nose-to-brain delivery of polymeric nanoparticles

, 2016
The difficulties encountered in the treatment of brain diseases with conventional pharmacological tools have created the need for innovative strategies. The combination of nanocarriers and alternative administration routes could represent an efficient approach to reach the brain.
DAL MAGRO, ROBERTA, Musumeci, T, Bonaccorso, A, DONZELLI, ELISABETTA, BALLARINI, ELISA, Puglisi, G, SANCINI, GIULIO ALFREDO   +6 more
openaire   +2 more sources

A novel and green nanoparticle formation approach to forming low-crystallinity curcumin nanoparticles to improve curcumin’s bioaccessibility [PDF]

, 2019
Health-promoting effects of curcumin are well-known; however, curcumin has a very low bioavailability due to its crystalline structure. The main objective of this study was to develop a novel green nanoparticle formation method to generate low ...
Ciftci, Ozan, Ubeyitogullari, Ali
core   +1 more source

Temporal Interference Stimulation Enhances Neural Regeneration

Advanced Science, EarlyView.
Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressott, Maria Garcia Garrido, Patrycja Dzialecka, Rachel Man Hoi Law, Roberto Portillo‐Lara, Bethany Geary, Elena Faillace, Shirine Merlo‐Nikpay Aslie, Marcelina Wojewska, Maria Otero‐Jimenez, Martina Genta, Luqiao Tan, Karen Duff, Javier Alegre‐Abarrategui, Rylie Green, Nir Grossmann   +15 more
wiley   +1 more source

Haploinsufficiency of Dmxl2, Encoding a Synaptic Protein, Causes Infertility Associated with a Loss of GnRH Neurons in Mouse [PDF]

, 2014
International audienceCharacterization of the genetic defects causing gonadotropic deficiency has made a major contribution to elucidation of the fundamental role of Kisspeptins and Neurokinin B in puberty onset and reproduction.
Carel, Jean-Claude, Charles, Perrine, Chevenne, Didier, Csaba, Zsolt, de Roux, Nicolas, Dupont, Joelle, Genin, Emmanuelle, Huijbregts, Lukas, Jacquier, Sandrine, Leka, Sofia, Léger, Juliane, Meyer, Vincent, Tata, Brooke   +12 more
core   +7 more sources

Artificial Piezoelectric Interface Enables Ultrafast Interfacial Ion Kinetic for Highly‐Sensitive Piezoionic Sensors

Advanced Science, EarlyView.
This study proposes a piezoelectric interface modification strategy to amplify the piezoionic effect. The piezoelectric interface generates an intrinsic electric field, which not only drives rapid ion migration but also concentrates polarized ions on the interface. The flexible sensor delivers superior performance, such as a quick response rate, strong
Yanyu Chen, Xingyue Ling, Rizhong Gao, Xiaohong Zhang, Xi Chen, Chao Lu   +5 more
wiley   +1 more source

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

“Will you be there for me?” Social support from family and friends during cold case sexual assault prosecutions

American Journal of Community Psychology, EarlyView.
Abstract If sexual assault survivors report the assault to the criminal legal system, they often need informal support from family and friends throughout the long and frequently retraumatizing process of investigation and prosecution. This study is part of a long‐term community‐based participatory action research project in a predominately Black ...
Rebecca Campbell, Rachael Goodman‐Williams, Katie Gregory, McKenzie Javorka, Jasmine Engleton   +4 more
wiley   +1 more source

Nasal Drug Delivery and Nose-to-Brain Delivery Technology Development Status and Trend Analysis: Based on Questionnaire Survey and Patent Analysis

Pharmaceutics
Nasal administration is a non-invasive method of drug delivery that offers several advantages, including rapid onset of action, ease of use, no first-pass effect, and fewer side effects.
Yuanyuan Ge, Xingying Xu, Meng Cao, Baijun Liu, Ying Wang, Ping Liao, Jiajing Wang, Yifei Chen, Hongmei Yuan, Guiliang Chen   +9 more
doaj   +1 more source

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12‐Related Developmental Disorders

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken, Miel Theunis, Kris Van den Bogaert, Koenraad Devriendt, Jeroen Breckpot   +4 more
wiley   +1 more source