Results 151 to 160 of about 566,967 (348)
Emerging structures and dynamic mechanisms of γ-secretase for Alzheimer’s disease
Neural Regeneration Researchγ-Secretase, called “the proteasome of the membrane,” is a membrane-embedded protease complex that cleaves 150+ peptide substrates with central roles in biology and medicine, including amyloid precursor protein and the Notch family of cell-surface ...
Yinglong Miao, Michael S. Wolfe
doaj +1 more source
Advanced Optical Materials, Volume 13, Issue 8, March 13, 2025.This article presents a hybrid metal‐dielectric metasurface in transmission mode for mid‐infrared (MIR) spectroscopy. Composed of germanium on aluminium cylinders atop a calcium fluoride substrate, the metasurface achieves 80% transmission efficiency at λ = 2.6 µm with a narrow full‐width‐half‐maximum of 0.4 µm.
Amr Soliman +5 more
wiley +1 more source
Cailiao gongchengWith the improvement in aeroengine performance，critical components （such as centrifugal impellers） operate under high-temperature，high-stress，and complex load conditions.
QUAN Changbiao +5 more
doaj +1 more source
Vat Photopolymerized HEMA/HEA Hydrogels for Solvent‐Responsive Transparency and Optical Encryption
Advanced Optical Materials, EarlyView.Vat‐photopolymerized HEMA/HEA hydrogels exhibit reversible transparency‐opacity switching via hydration‐induced microphase separation and solvent exchange. The printed materials enable hydration sensing, optical encryption, and information storage, while maintaining high ductility and reversible rheology.
Murad Ali +4 more
wiley +1 more source
Micromachined Double‐Membrane Mechanically Tunable Metamaterial for Thermal Infrared Filtering
Advanced Photonics Research, Volume 6, Issue 5, May 2025.Herein, a mechanically tunable double‐layer plasmonic metamaterial leveraging the extraordinary optical transmission effect observed in subwavelength arrays of openings within thin metal layers is presented. The concept is experimentally validated by integrating the proposed metamaterial structure into an electrostatic parallel‐plate actuator to create
Oleg Bannik +7 more
wiley +1 more source
Specimen size and geometry effects on fracture toughness of Al2O3 measured with short rod and short bar chevron-notch specimens [PDF]
Plane strain fracture toughness measurements were made on Al2O3 using short rod and short bar chevron notch specimens previously calibrated by the authors for their dimensionless stress intensity factor coefficients.
Munz, D. G., Shannon, J. L., Jr.
core +1 more source
Continuum Mechanics Modeling of Flexible Spring Joints in Surgical Robots
Advanced Robotics Research, EarlyView.A new mechanical model of a tendon‐actuated helical extension spring joint in surgical robots is built using Cosserat rod theory. The model can implicitly handle the unknown contacts between adjacent coils and numerically predict spring shapes from straight to significantly bent under actuation forces.
Botian Sun +3 more
wiley +1 more source
Advanced Science, EarlyView.Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck +8 more
wiley +1 more source