Results 71 to 80 of about 566,967 (348)

Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine KrasG12D-induced skin carcinogenesis in vivo [PDF]

, 2010
Background The Ras and Notch signaling pathways are frequently activated during development to control many diverse cellular processes and are often dysregulated during tumorigenesis.
Barbara M. Grüner, Bence Sipos, Freddy Radtke, Hassan Nakhai, Jens T. Siveke, Joseph Alan Bauer, Lothar J. Strobl, Pawel K. Mazur, Roland M. Schmid, Ursula Zimber-Strobl   +9 more
core   +4 more sources

Viral transduction of primary human lymphoma B cells reveals mechanisms of NOTCH-mediated immune escape [PDF]

, 2022
Maurizio Mangolini, Alba Maiqués-Díaz, Stella Charalampopoulou, Elena Hartmann, Johannes Bloehdorn, A. P. Moore, Giorgia Giachetti, Junyan Lu, Valar Nila Roamio Franklin, Chandra Sekkar Reddy Chilamakuri, Ilias Moutsopoulos, Andreas Rosenwald, Stephan Stilgenbauer, Thorsten Zenz, Irina Mohorianu, Clive S. D’Santos, Silvia Deaglio, Daniel J. Hodson, José I. Martı́n-Subero, Ingo Ringshausen   +19 more
openalex   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Effects of crocin on the enhancement of in vitro neurogenesis: Involvement of Notch and CREB/BDNF signaling pathways [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Adult neurogenesis, the process of generating new neurons, continues throughout life. Unfortunately, this process is insufficient in pathological conditions and needs to be promoted.
Shayan Vafaei, Vida Mirzaie, Masoumeh Baghalishahi, Elahe Mousanejad, Seyed Noureddin Nematollahi-mahani   +4 more
doaj   +1 more source

Apparatus and method for explosive bonding to edge of flyer plate [PDF]

, 1991
The invention is an apparatus and a process for the explosive joining of a flyer plate and a base plate. The apparatus consists of a flyer plate positioned over a base plate.
Bement, Laurence J., Kushnick, Anne C.
core   +1 more source

Images of the Dark Soliton in a Depleted Condensate

, 2003
The dark soliton created in a Bose-Einstein condensate becomes grey in course of time evolution because its notch fills up with depleted atoms. This is the result of quantum mechanical calculations which describes output of many experimental repetitions ...
, Burger S, Bush Th, Castin Y, Castin Y, Castin Y, Dalfovo F, Dobrek L, Dziarmaga J, Gardiner C W, Girardeau M D, Girardeau M D, Gross E P, Jacek Dziarmaga, Javanainen J, Krzysztof Sacha, Law C K, Leggett A J, Muryshev A E, Naraschewski M, Pitaevskii L P, Taylor J K (ed), Zbyszek P Karkuszewski   +22 more
core   +1 more source

Notch signaling during human T cell development [PDF]

, 2012
Notch signaling is critical during multiple stages of T cell development in both mouse and human. Evidence has emerged in recent years that this pathway might regulate T-lineage differentiation differently between both species.
A Galy, A Krueger, A Sambandam, A Wilson, A Wolfer, AC Jaleco, AI Garbe, AP Weng, B Blom, B Reizis, B Vandekerckhove, BN Weber, C Benne, CC Tydell, CN Ting, D Hockemeyer, D Hockemeyer, E Robey, EM Six, ES David-Fung, F Klein, F Radtke, F Radtke, F Timmermans, F Weerkamp, F Weerkamp, G Awong, H Hirata, H Neves, H Wang, HT Petrie, HY Kueh, I Hoebeke, I Maillard, I Maillard, I Walle Van de, I Walle Van de, J Buer, J Gotter, J Plum, J Shi, JS Yuan, K Heinzel, K Hozumi, K Li, K Maki, K Tanigaki, L Li, M Ciofani, M Ciofani, M Ciofani, M Garcia-Peydro, M Ghisi, M Magri, M Smedt De, M Smedt De, M Smedt De, M Smedt De, MA Yui, MD Green, ML Joachims, N Lefort, P Beatus, P Doerfler, P Li, QL Hao, QL Hao, R Haddad, RN Motte-Mohs La, S Coppernolle Van, S Doulatov, S Gonzalez-Garcia, S Suliman, S Verbeek, SK Durum, SK Ye, SM Lehar, SY Lee, T Hosoya, T Ikawa, T Ikawa, T Kreslavsky, T Kreslavsky, T Palomero, T Taghon, T Taghon, T Taghon, T Taghon, T Taghon, T Taghon, TB Feyerabend, TM Schmitt, TN Taghon, W Dontje, WA Dik, Y Wu, YR Carrasco, Z Galic   +97 more
core   +2 more sources

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Short crack initiation and growth at 600 °C in notched specimens of Inconel718

, 2003
The natural initiation and growth of short cracks in Inconel®718 U-notch specimens has been studied at 600 °C in air. U notches were introduced through broaching, and hardness traces and optical microscopy on cross-sections through the U notch broaching ...
Connolley, T., Reed, P.A.S., Starink, M.J.   +2 more
core   +1 more source

Evaluation of the Potential of Laser Shock Peening Compared with Cold Expansion for Improving Fatigue Resistance of Riveted Lap Joints of Aerospace Grade 7175 Al Alloy

Advanced Engineering Materials, EarlyView.
This study investigates laser shock peening for enhancing fatigue performance of riveted aerospace aluminum joints. A comparative approach with cold expansion combines fatigue testing and synchrotron X‐ray methods. Integrating mechanical testing with residual stress and strain characterization provides insights into how different treatments affect the ...
Ogün Baris Tapar, David Osman Busse, Maximilian Sprengel, Domenico Furfari, Marc‐André Nielsen, Guilherme Abreu Faria, Jérémy Epp   +6 more
wiley   +1 more source