Results 61 to 70 of about 196,993 (268)

Rafting of Ni‐Based Superalloys Under Multiaxial Load as Understood by Phase‐Field Simulations and Critical Experiments

open access: yesAdvanced Engineering Materials, EarlyView.
Phase‐field simulations coupled with dislocation‐density‐based crystal plasticity modeling reproduce γ′ rafting behavior in single‐crystal Ni‐based superalloys under varied loading conditions. The model captures both macroscopic creep and microscopic morphology evolution, with results matching high‐temperature creep experiments.
Micheal Younan   +5 more
wiley   +1 more source

Notch Signaling in Kidney Development, Maintenance, and Disease

open access: yesBiomolecules, 2019
Kidney development involves formation of nephrons intricately aligned with the vasculature and connected to a branched network of collecting ducts.
Malini Mukherjee   +3 more
doaj   +1 more source

Notching on Cancer’s Door: Notch Signaling in Brain Tumors [PDF]

open access: yesFrontiers in Oncology, 2015
Notch receptors play an essential role in the regulation of central cellular processes during embryonic and postnatal development. The mammalian genome encodes for four Notch paralogs (Notch 1-4), which are activated by three Delta-like (Dll1/3/4) and two Serrate-like (Jagged1/2) ligands.
Teodorczyk, Marcin, Schmidt, Mirko HH
openaire   +4 more sources

Karl Popper and the Mechanisms of Hydrogen Embrittlement

open access: yesAdvanced Engineering Materials, EarlyView.
Representation of the beginning of loss of ductility rather than embrittlement. Small concentrations of hydrogen in a diffusible form within iron are well‐established to harm the mechanical integrity of steels. There are theories that attempt to explain the pernicious role of hydrogen.
H. K. D. H. Bhadeshia
wiley   +1 more source

To Be, Notch to Be [PDF]

open access: yesIndian Journal of Plastic Surgery, 2020
Moumita De   +4 more
openaire   +3 more sources

Microstructure‐Controlled Crack Propagation and Fracture Resistance in MoSiBTiC Alloy Revealed by Multiscale Extended Finite Element Method Modeling

open access: yesAdvanced Engineering Materials, EarlyView.
A two‐dimensional multiscale finite element analysis framework was established for the first‐generation MoSiBTiC alloy, and the mechanical and fracture‐related parameters of the constituent phases were calibrated through experiments and simulations. The framework provides a basis for analyzing crack propagation behavior in its complex microstructure ...
Junfeng Du   +4 more
wiley   +1 more source

Non-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent

open access: yeseLife, 2016
β-selection is the most pivotal event determining αβ T cell fate. Here, surface-expression of a pre-T cell receptor (pre-TCR) induces thymocyte metabolic activation, proliferation, survival and differentiation.
Luise Westernberg   +9 more
doaj   +1 more source

"Notch-Off": a perspective on the termination of Notch signalling

open access: yesThe International Journal of Developmental Biology, 2009
During Notch mediated lateral inhibition, interacting cells establish or amplify differences in Notch signalling, which are then translated into distinct cell fate decisions according to the developmental context. In recent years, several mechanisms that increase the signalling capacity of interacting cells have been uncovered (reviewed in Bray, 2006 ...
Rita, Fior, Domingos, Henrique
openaire   +3 more sources

Fatigue Crack Initiation and Growth in Nanocrystalline Ni at Multiple Length‐Scales

open access: yesAdvanced Engineering Materials, EarlyView.
Overview of miniaturized in situ SEM fatigue setup and resultant fatigue crack growth data for nanocrystalline Ni. The presented study focuses on the analysis of fatigue crack growth rate (FCGR) in focused ion beam‐notched microcantilevers prepared from nanocrystalline (NC) Ni as a model material.
Igor Moravcik   +7 more
wiley   +1 more source

Special Issue on Fracture and Fatigue Assessments of Structural Components

open access: yesApplied Sciences, 2020
This Special Issue covers the broad topic of structural integrity of components subjected to either static or fatigue loading conditions, and it is concerned with the modelling, assessment and reliability of components of any scale. Dealing with fracture
Alberto Campagnolo
doaj   +1 more source

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