Results 171 to 180 of about 118,516 (288)

The Dual Immunoregulatory Role of CREB3L1 Underlying Latent and Severe Tuberculosis Clinical Manifestation

open access: yesImmunology, EarlyView.
RNA‐seq of lungs and livers from Mycobacterium tuberculosis‐infected mice with distinct disease outcomes revealed organ‐specific responses driven by differences in immune activity and bacterial burden. Meta‐analysis identified orthologous genes shared with human latent TB and mouse liver, with Creb3l1, Myo7b, Cyyr1 and Cbs differentially expressed and ...
Felipe T. Lima   +9 more
wiley   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

open access: yesJournal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag   +6 more
wiley   +1 more source

Lats1/2 Differentially Modulate the Proliferative State of Dental Epithelial Progenitors and Ameloblasts in the Murine Incisor

open access: yesOrthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective(s) Yes‐Associated Protein (YAP) is a critical regulator of cell proliferation and differentiation, having the capacity to convert differentiated cells into somatic stem cells in several contexts. Here we investigate the plasticity of adult mouse dental epithelial cells by testing the effects of ectopic YAP activation in dental ...
Zhiyue Zhang   +4 more
wiley   +1 more source

Cancer Hallmarks Expression in Oral Leukoplakia: Systematic Review and Meta‐Analysis

open access: yesOral Diseases, EarlyView.
ABSTRACT Objectives To assess the available evidence on the expression of hallmarks of cancer and oral leukoplakia (OL) malignant transformation probability, with the goal of identifying the earliest oncogenic molecular events participating in oral cancer carcinogenesis.
I. González‐Ruiz   +4 more
wiley   +1 more source

Notch 1 (NOTCH1) [PDF]

open access: yesScience-Business eXchange, 2014
openaire   +1 more source

Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next

open access: yesPhotochemistry and Photobiology, EarlyView.
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal   +3 more
wiley   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

open access: yesPhotochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew   +3 more
wiley   +1 more source

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