Results 91 to 100 of about 14,274 (181)

Protein aggregates containing wild-type and mutant NOTCH3 are major drivers of arterial pathology in CADASIL

The Journal of Clinical Investigation
Loss of arterial smooth muscle cells (SMCs) and abnormal accumulation of the extracellular domain of the NOTCH3 receptor (Notch3ECD) are the 2 core features of CADASIL, a common cerebral small vessel disease caused by highly stereotyped dominant ...
Nicolas Dupré, Florian Gueniot, Valérie Domenga-Denier, Virginie Dubosclard, Christelle Nilles, David Hill-Eubanks, Christelle Morgenthaler-Roth, Mark T. Nelson, Céline Keime, Lydia Danglot, Anne Joutel   +10 more
doaj   +1 more source

Prognostic Significance of <i>NOTCH3</i> Small Vessel Disease Staging for the <i>NOTCH3</i> p.R544C Variant. [PDF]

Neurol Genet
Shen YC, Chen CH, Chen HC, Cheng YW, Chang CY, Kuo PH, Chen YM, Lee WJ, Tang SC.   +8 more
europepmc   +1 more source

An in trans NOTCH3 loss-of-function variant modifies disease severity in CADASIL: A family-based study. [PDF]

J Chin Med Assoc
Lan SC, Liu YH, Lan J, Liao YC, Lan MY, Lee YC, Lee YC.   +6 more
europepmc   +1 more source

Notch 3 (NOTCH3) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

3D Vessels-on-Chip using isogenic hiPSC-derived VSMCs reveal NOTCH3-driven alterations in brain small vessel disease. [PDF]

Stem Cell Reports
Vila Cuenca M, Tsikari T, Cerfontaine MN, Gallant JL, van den Hil FE, Bouma MJ, Dijkstra KL, Gravesteijn G, de Vries AAF, Mummery CL, Rutten JW, Lesnik Oberstein SAJ, Orlova VV.   +12 more
europepmc   +1 more source

NOTCH3 Gene Mutation [PDF]

, 2020
openaire   +1 more source

New Insights into the Development of Papillary Thyroid Cancer: The Roles of miR-1179 and ELF3. [PDF]

Cells
Henry N, Bahassou N, Libert F, Dom G, Maenhaut C.   +4 more
europepmc   +1 more source

NOTCH3 attenuates cytotoxicity via RBPJ-dependent PVR upregulation to influence immunotherapy outcomes in colorectal cancer. [PDF]

Front Immunol
Ma Q, Xu S, Ma N, Li K, Liu Y, Ma F.
europepmc   +1 more source

Functional analysis of the human miRNome in non-small cell lung cancer unveils a novel miR-92b-3p/NOTCH3 axis that drives tumor progression. [PDF]

Cell Death Dis
Cuttano R, Afanga MK, Longo F, Di Cillo N, Melocchi V, Dama E, Mazzarelli F, Palumbo P, Bertalot G, Bianchi F.   +9 more
europepmc   +1 more source

NOTCH3 Mutations in CADASIL: a multicellular perspective on neurodegeneration. [PDF]

Cell Commun Signal
Lee JWL, Ng ASL, Tan EK, Zeng L.
europepmc   +1 more source