Results 91 to 100 of about 16,426 (214)
Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.The progression of silicosis‐associated fibrosis relies on a positive feedback loop mediated by crosstalk between Cxcr4+ macrophages and Cxcl12+ fibroblasts and the therapeutic potential of targeting the Cxcl12/Cxcr4 axis with AMD3100 as a novel strategy for treating silicosis.
Min Mu +11 more
wiley +1 more source
Clearance of mutant NOTCH3 proteins.
, 2012 293 cells (n = 3 replicate wells per group) were transiently transfected with NOTCH3-luciferase constructs and split into identical 24 well chambers after 24 hours.
He Meng (33363) +6 more
core +1 more source
Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma
eFood, Volume 7, Issue 3, June 2026.Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie +5 more
wiley +1 more source
Notch3 signaling and vascular remodeling in pulmonary arterial hypertension [PDF]
, 2019 Notch signalling is critically involved in vascular morphogenesis and function. Four Notch isoforms (Notch1–4) regulating diverse cellular processes have been identified.
Neves, Karla B. +4 more
core +1 more source
NOTCH3 regulates stem-to-mural cell differentiation in infantile hemangioma
, 2018 Infantile hemangioma (IH) is a vascular tumor that begins with rapid vascular proliferation shortly after birth, followed by vascular involution in early childhood.
Kitajewski, Alison A. +11 more
core +1 more source
Journal of Translational MedicineBackground Chronic pancreatitis (CP) is characterized by progressive fibrosis and the activation of pancreatic stellate cells (PSCs). As major producers of collagen-I and fibronectin, PSCs play important roles in pancreatic fibrosis, but few studies have
Zheng Lian +3 more
doaj +1 more source
Prominent juxtacortical white matter lesion hallmarks NOTCH3-related intracerebral haemorrhage
Stroke and Vascular NeurologyBackground and purpose NOTCH3 p.R544C mutation accounts for 5% of spontaneous intracerebral haemorrhage (ICH) in East Asian patients. We investigated whether certain CT features are associated with NOTCH3-related ICH.Methods Patients with spontaneous ICH
Sung-Chun Tang +5 more
doaj +1 more source
Notch3 signaling pathway in cerebral arteries
, 2012 Le gène Notch3 code pour un récepteur transmembranaire hétérodimérique exprimé principalement dans les cellules musculaires lisses des petites artères.
Fouillade, Charles
core
Notch3 in normal pancreas and PDAC.
, 2013 a) Notch3 in the cytoplasm of normal pancreatic ductal epithelial cells; b) resected PDAC demonstrating strong cytoplasmic Notch3 with some positive nuclei; c) resected PDAC demonstrating largely nuclear stain; d) nuclear stain in an area of perineural ...
Christopher D. Mann (295856) +9 more
core +1 more source
Clinical presentation of Y189C mutation of the NOTCH3 gene in the Polish family with CADASIL
Folia Neuropathologica, 2020 Jolanta Dorszewska +8 more
doaj +1 more source