Results 111 to 120 of about 16,426 (214)

Myofibrillogenesis Regulator‐1 Regulates the Ubiquitin Lysosomal Pathway of Notch3 Intracellular Domain Through E3 Ubiquitin‐Protein Ligase Itchy Homolog in the Metastasis of Non‐Small Cell Lung Cancer

open access: yesAdvanced Science
Myofibrillogenesis regulator‐1 (MR‐1) is a multifunctional protein involved in the development of various human tumors. The study is the first to report the promoting effect of MR‐1 on the development and metastasis of non‐small cell lung cancer (NSCLC).
Wenxia Zhao   +11 more
doaj   +1 more source

Rôle de Notch3 dans la microcirculation rénale

open access: yes, 2009
Notch3 est une protéine membranaire impliquée dans la différenciation des cellules musculaires lisses et la régulation du réflexe myogénique cérébral. L objectif de ce travail est de préciser le rôle de Notch3 dans la microcirculation rénale.
CHATZIANTONIOU, Christos, BOULOS, Nada
core  

The Notch3 receptor and its intracellular signaling-dependent oncogenic mechanisms

open access: yes, 2018
During evolution, gene duplication of the Notch receptor suggests a progressive functional diversification. The Notch3 receptor displays a number of structural differences with respect to Notch1 and Notch2, most of which have been reported in the ...
Isabella Screpanti   +3 more
core   +1 more source

NOTCH3 knockdown in U87-MG and U251-MG cells reduced expression of NOTCH3 and its target.

open access: yes, 2013
(A) Western blot of U87-MG and U251-MG cells showing silencing of NOTCH3 protein expression at both full length and cleaved forms following shRNA treatment. GAPDH was used as loading control.
Timothy C. Ryken (413028)   +5 more
core   +1 more source

An overview of Notch3 function in vascular smooth muscle cells

open access: yes, 2008
Proteins of the Notch family are cell surface receptors that transduce signals between neighbouring cells. The Notch signalling pathway is highly evolutionarily conserved and critical for cell fate determination during embryonic development, including ...
Baron, Martin; id_orcid   +5 more
core   +1 more source

NOTCH3 as a prognostic biomarker and its correlation with immune infiltration in gastrointestinal cancers

open access: yesScientific Reports
NOTCH receptor 3 (NOTCH3) is known to regulate the transcription of oncogenes or tumor suppressor genes, thereby playing a crucial role in tumor development, invasion, maintenance, and chemotherapy resistance.
Jia Xu   +7 more
doaj   +1 more source

ISEV2026 Abstract Book

open access: yes
Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

Voie de signalisation Notch3 dans les artères cérébrales

open access: yes, 2012
Le gène Notch3 code pour un récepteur transmembranaire hétérodimérique exprimé principalement dans les cellules musculaires lisses des petites artères.
JOUTEL, Anne, FOUILLADE, Charles
core  

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