Results 121 to 130 of about 23,019 (220)

NOTCH3 as a prognostic biomarker and its correlation with immune infiltration in gastrointestinal cancers

Scientific Reports
NOTCH receptor 3 (NOTCH3) is known to regulate the transcription of oncogenes or tumor suppressor genes, thereby playing a crucial role in tumor development, invasion, maintenance, and chemotherapy resistance.
Jia Xu, Xiao-li Jin, Hao Shen, Xuan-wei Chen, Jin Chen, Hui Huang, Bin Xu, Jian Xu   +7 more
doaj   +1 more source

A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma

Haematologica
Multiple myeloma (MM) remains incurable due to disease relapse and drug resistance. Notch signals from the tumor microenvironment (TME) confer chemoresistance, but the cellular and molecular mechanisms are not entirely understood.
Hayley M. Sabol, Cody Ashby, Manish Adhikari, Aric Anloague, Japneet Kaur, Sharmin Khan, Samrat Roy Choudhury, Carolina Schinke, Michela Palmieri, C. Lowry Barnes, Elena Ambrogini, Intawat Nookaew, Jesus Delgado-Calle   +12 more
doaj   +1 more source

Computer identification of Notch3 in the neurogenic progenitor cells of mammalian early optic vesicles

BMC Research Notes
Objective The developing mammalian retina initially contains undifferentiated cells, providing a model for investigating the mechanisms of differentiation.
Yoshitoku Watabe, Sakurako Kobayashi, Satoru Takahashi, Masaharu Yoshihara   +3 more
doaj   +1 more source

NOTCH3 Gene Mutation [PDF]

, 2020
openaire   +1 more source

NOTCH3 wt Allele [PDF]

, 2020
openaire   +1 more source

Protein aggregates containing wild-type and mutant NOTCH3 are major drivers of arterial pathology in CADASIL

The Journal of Clinical Investigation
Loss of arterial smooth muscle cells (SMCs) and abnormal accumulation of the extracellular domain of the NOTCH3 receptor (Notch3ECD) are the 2 core features of CADASIL, a common cerebral small vessel disease caused by highly stereotyped dominant ...
Nicolas Dupré, Florian Gueniot, Valérie Domenga-Denier, Virginie Dubosclard, Christelle Nilles, David Hill-Eubanks, Christelle Morgenthaler-Roth, Mark T. Nelson, Céline Keime, Lydia Danglot, Anne Joutel   +10 more
doaj   +1 more source

Notch 3 (NOTCH3) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

NOTCH3-related CADASIL and Non-NOTCH3-related CADASIL-like syndrome

Nosotchu, 2008
Toshiki Mizuno, Akiko Hosomi, Yoshinari Nagakane, Fumiko Oshima, Hidekazu Tomimoto, Masanori Nakagawa   +5 more
openaire   +2 more sources

Prognostic Significance of <i>NOTCH3</i> Small Vessel Disease Staging for the <i>NOTCH3</i> p.R544C Variant. [PDF]

Neurol Genet
Shen YC, Chen CH, Chen HC, Cheng YW, Chang CY, Kuo PH, Chen YM, Lee WJ, Tang SC.   +8 more
europepmc   +1 more source

Notch 3 (NOTCH3) [PDF]

Science-Business eXchange, 2013
openaire   +1 more source