Results 101 to 110 of about 23,019 (220)
Mediators of Inflammation, 2016 Notch3 and pS6 play important roles in tumor angiogenesis. To assess the expression of Notch3 and pS6 in Chinese ovarian epithelial cancer patients, a ten-year follow-up study was performed in ovarian epithelial cancer tissues from 120 specimens of human
Zhaoxia Liu +6 more
doaj +1 more source
Notch signaling in serous ovarian cancer [PDF]
, 2014 Ovarian cancer is the most lethal of all gynecologic malignancies because women commonly present with advanced stage disease and develop chemotherapy refractory tumors.
Foster, Rosemary +4 more
core +1 more source
Targeted Therapy and Immunotherapies in Hepatocellular Carcinoma: Mechanisms and Clinical Studies
MedComm, Volume 7, Issue 5, May 2026.The mechanism of multiple signaling pathways and their related targeted inhibitors in HCC. (A) The mechanism of Ras/Raf/MEK/ERK signaling pathway and its related targeted inhibitors; (B) the mechanism of PI3K/AKT/mTOR signaling pathway and its crosstalk with other pathways and its related targeted inhibitors; (C) the mechanism of JAK/STAT signaling ...
Penghui He +9 more
wiley +1 more source
RNA Modifications: Current Understandings and Future Perspectives
MedComm, Volume 7, Issue 5, May 2026.Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao +7 more
wiley +1 more source
Clinical and Genetic Landscape of Glioblastoma, IDH‐Wildtype With FGFR Gene Family Alterations
Cancer Science, Volume 117, Issue 5, Page 1455-1468, May 2026.We analyzed 1076 cases of glioblastoma, IDH‐wildtype (GBM, IDH‐wt) using the C‐CAT genomic database to clarify the clinical and genetic features of FGFR alterations. FGFR::TACC fusions and FGFR1 mutations were identified in distinct subsets and were associated with unique co‐mutation patterns.
Yasuhito Kegoya +9 more
wiley +1 more source
Journal of Clinical Periodontology, Volume 53, Issue 5, Page 806-820, May 2026.ABSTRACT Aim To investigate the intra‐tissue bacteriome and cell profiles within periodontal granulation tissue (PGT) for exploring the biological essence and translational potentials. Materials and Methods PGT samples were collected from 49 patients with severe periodontitis—including those from osseous defects (GT) during periodontal surgery ...
Tianfan Cheng +9 more
wiley +1 more source
Di-san junyi daxue xuebao, 2019 Objective To investigate the clinicopathological features of osteosarcoma and the prognostic significance of the expression of Notch receptors and ligands.
TANG Xuefeng, ZENG Ying, WANG Yali
doaj +1 more source
Chemotactic Cues for NOTCH1-Dependent Leukemia [PDF]
, 2018 The NOTCH signaling pathway is a conserved signaling cascade that regulates many aspects of development and homeostasis in multiple organ systems.
Amadori, Alberto +3 more
core +1 more source
The FASEB Journal, Volume 40, Issue 8, 30 April 2026.The purification protocol for hypertrophied hepatic stellate cells (hypHSCs) developed in this study, using fibrotic and steatotic mouse livers (CDAHFD model), made it possible to obtain a high‐purity hypHSC preparation for transcriptomic analysis.
Marion Heckmann +9 more
wiley +1 more source
Novel mechanism of resistance to targeted therapies in lung cancer
Molecular & Cellular Oncology, 2019 We have identified a non-canonical role of0 Notch3 in response to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) therapy, whereby Notch3 associates with β-catenin, resulting in increased catenin beta-1 (CTNNB1, best known as β ...
Walter Wang +2 more
doaj +1 more source