Results 81 to 90 of about 98,277 (259)
Advanced Materials, EarlyView.Elephant‐skin‐inspired crack networks are programmed in porous diatomaceous earth (DE)‐cement composites using substrate‐guided, stress‐concentration induced fracture. The resulting crack lattices act as capillary conduits that redistribute water, while the porous matrix stores moisture.
Qingya Huang +5 more
wiley +1 more source
Advanced Materials, EarlyView.Mechanically origami‐coded 3D kirigami photovoltaics convert a single extension–release cycle into deterministic self‐folding, reconfiguring planar solar cells into programmable 3D modules. Distinct coding strategies enable either ultrahigh stretchability (500% system strain) or ultrahigh initial effective areal coverage (225%).
Seok Joon Hwang +15 more
wiley +1 more source
Advanced Materials, EarlyView.Inspired by Acorus calamus leaves, a heterogeneous eutectic skin integrates an aligned fibrous network within a hydrophobic eutectogel matrix. This hierarchical architecture triggers strain‐induced crystallization to achieve exceptional mechanical toughness and durable wet adhesion.
Jiayu Hou +16 more
wiley +1 more source
Notch Regulates Macrophage-Mediated Inflammation in Diabetic Wound Healing
Frontiers in Immunology, 2017 Macrophages are essential immune cells necessary for regulated inflammation during wound healing. Recent studies have identified that Notch plays a role in macrophage-mediated inflammation.
Andrew S. Kimball +11 more
doaj +1 more source
Advanced Materials Technologies, EarlyView.This work highlights the impact of incorporating graphene nanoflakes into precursor inks of MAPbBr3 for inkjet‐printed optoelectronic device applications. A substantial modification of the crystallization dynamics is reported despite miniscule concentrations.
Kenneth Lobo +12 more
wiley +1 more source
Non-canonical Notch signaling drives activation and differentiation of peripheral CD4+ T cells
Frontiers in Immunology, 2014 Cleavage of the Notch receptor via a γ-secretase, results in the release of the active intra-cellular domain of Notch that migrates to the nucleus and interacts with RBP-JΚ, resulting in the activation of downstream target genes.
Anushka eDongre +10 more
doaj +1 more source
ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells
Advanced Science, EarlyView.With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao +16 more
wiley +1 more source
Notch signaling pathway in cancer: from mechanistic insights to targeted therapies
Signal Transduction and Targeted TherapyNotch signaling, renowned for its role in regulating cell fate, organ development, and tissue homeostasis across metazoans, is highly conserved throughout evolution.
Qingmiao Shi +9 more
doaj +1 more source
The Notch Signaling Pathway: Mechanistic Insights in Health and Disease
EngineeringThe Notch signaling pathway is evolutionarily conserved across metazoan species and plays key roles in many physiological processes. The Notch receptor is activated by two families of canonical ligands (Delta-like and Serrate/Jagged) where both ligands ...
Yao Meng +4 more
doaj +1 more source
A novel reporter allele for monitoring Dll4 expression within the embryonic and adult mouse
Biology Open, 2018 Canonical Notch signaling requires the presence of a membrane bound ligand and a corresponding transmembrane Notch receptor. Receptor engagement induces multiple proteolytic cleavage events culminating in the nuclear accumulation of the Notch ...
Alexander M. Herman +5 more
doaj +1 more source