Results 11 to 20 of about 150,664 (297)
NOTCH activity differentially affects alternative cell fate acquisition and maintenance [PDF]
eLife, 2018 The pituitary is an essential endocrine gland regulating multiple processes. Regeneration of endocrine cells is of therapeutic interest and recent studies are promising, but mechanisms of endocrine cell fate acquisition need to be better characterised ...
Leonard Cheung +5 more
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Control of Neural Daughter Cell Proliferation by Multi-level Notch/Su(H)/E(spl)-HLH Signaling. [PDF]
PLoS Genetics, 2016 The Notch pathway controls proliferation during development and in adulthood, and is frequently affected in many disorders. However, the genetic sensitivity and multi-layered transcriptional properties of the Notch pathway has made its molecular decoding
Caroline Bivik +5 more
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Notch sensitivity of mammalian mineralized tissues in impact [PDF]
Proceedings of the Royal Society of London. Series B: Biological Sciences, 2004 The toughness of bone is an important feature in preventing it from fracturing. We consider the notch sensitivity in impact, and the associations between brittleness, notch sensitivity and post-yield energy absorption of mammalian mineralized tissues. Specimens of bone-like tissues covering a wide range of mineralization were broken, either notched or ...
Currey, John D. +2 more
openaire +7 more sources
Cis-activation in the Notch signaling pathway [PDF]
eLife, 2019 The Notch signaling pathway consists of transmembrane ligands and receptors that can interact both within the same cell (cis) and across cell boundaries (trans). Previous work has shown that cis-interactions act to inhibit productive signaling.
Nagarajan Nandagopal +2 more
doaj +4 more sources
Computational Screening of Tip and Stalk Cell Behavior Proposes a Role for Apelin Signaling in Sprout Progression [PDF]
, 2016 Angiogenesis involves the formation of new blood vessels by sprouting or splitting of existing blood vessels. During sprouting, a highly motile type of endothelial cell, called the tip cell, migrates from the blood vessels followed by stalk cells, an ...
Dallinga, Marchien G. +5 more
core +8 more sources
Influence of microstructure on fatigue property of ultra high-strength steels
Fracture and Structural Integrity, 2019 Ultra-high-strength steels (with tensile strength higher than 980 MPa) are widely used in automobile manufacturing owing to their lightweight that contributes to fuel efficiency.
Kanji OKUDA +4 more
doaj +3 more sources
Notch sensitivity of metamaterial with snapping microstructure
Nihon Kikai Gakkai ronbunshu, 2020 The purpose of this project is to examine the notch sensitivity to the strength of a mechanical metamaterial comprising a periodic arrangement of snapping units.
Ken HIKASA +4 more
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Apnea detection from photoplethysmography signal using dicrotic notch
Current Directions in Biomedical Engineering, 2022 Photoplethysmography signal (PPG) provides information about the cardiovascular, respiratory, or nervous system activity. Recent studies proposed methods of apnea identification from PPG using amplitude or baseline modulation, or area under the curve. We
Rafl-Huttova Veronika +3 more
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Fatigue notch sensitivity of steel blunt‐notched specimens
Fatigue & Fracture of Engineering Materials & Structures, 2002 ABSTRACTThe notch sensitivity of three steels with similar plain fatigue limits was analysed and modelled. The analysis was made by using a model previously derived which estimated the fatigue limit of blunt notched components by means of the parameter ktd defined as the stress concentration introduced by the notch at a distance d from the notch root ...
Chapetti, Mirco Daniel +2 more
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Mechanical Properties and Notch Sensitivities of the Hydrogenated X70 Pipeline Steel Welded Joints [PDF]
Cailiao BaohuIn order to explore the effects of pipeline inner-wall surface defects on reliability of the hydrogen enriched compressed natural gas(HCNG) pipeline steel welded joints in long-term service， the notches in the base metal， weld seam and heat affected zone
CHEN Ye, WANG Wanli, ZHAN Xianqiang, LIU Junjian, TANG Wenming
doaj +1 more source