Results 11 to 20 of about 1,914,304 (195)

Effects of pressure sensitivity and notch geometry on notch‐tip fields [PDF]

Polymer Engineering & Science, 1998
AbstractPlane‐strain stress and slip‐line fields near the sharp and round tips of wedge‐shaped notches in perfectly plastic pressure‐sensitive materials are investigated to illustrate the effects of pressure sensitivity and notch geometry on notch‐tip fields.
Al-Abduljabbar, A., Pan, Jwo
openaire   +4 more sources

Notch sensitivity of mammalian mineralized tissues in impact [PDF]

Proceedings of the Royal Society of London. Series B: Biological Sciences, 2004
The toughness of bone is an important feature in preventing it from fracturing. We consider the notch sensitivity in impact, and the associations between brittleness, notch sensitivity and post-yield energy absorption of mammalian mineralized tissues. Specimens of bone-like tissues covering a wide range of mineralization were broken, either notched or ...
Currey, John D., Brear, Kevin, Zioupos, Peter   +2 more
openaire   +7 more sources

Assessing the Notch Sensitivity of High Strength Wires

Latin American Journal of Solids and Structures
High strength wires, which have a poor notch sensitivity performance, are currently been used on many offshore applications where high stresses without yielding are demanded. To assess these wires notch sensitivity, an integrated approach was implemented.
Carlos Filipe Cardoso Bandeira, Paulo Pedro Kenedi, Luis Felipe Guimarães de Souza   +2 more
doaj   +2 more sources

The interaction of Notch signalling, haemodynamic flow and angiogenesis in Von Hippel-Lindau mutant zebrafish. [PDF]

, 2013
Introduction: There is increasing evidence that the endothelium is able to transduce circulatory force into signals which influence angiogenic behaviour.
Watson, Oliver
core   +6 more sources

miR-27-3p Enhances the Sensitivity of Triple-Negative Breast Cancer Cells to the Antitumor Agent Olaparib by Targeting PSEN-1, the Catalytic Subunit of Γ-Secretase

Frontiers in Oncology, 2021
Olaparib has been used in the treatment of triple-negative breast cancer (TNBC) with BRCA mutations. In the present study, we demonstrated the effect of miR-27-3p on the γ-secretase pathway by regulating the sensitivity of TNBC cells to olaparib.
Meng Zhao, Baisheng Sun, Yan Wang, Gengbao Qu, Hua Yang, Pilin Wang   +5 more
doaj   +1 more source

On the notch sensitivity of cast iron under multi-axial fatigue loading [PDF]

Fracture and Structural Integrity, 2014
This work deals with the notch sensitivity of sharp notches under multi-axial fatigue loading. The main discussion concerns the differences in notch sensitivity at high cycle fatigue regime, between tensile, torsional and combined loading.
P. Livieri, E. Maggiolini, R. Tovo
doaj   +3 more sources

Apnea detection from photoplethysmography signal using dicrotic notch

Current Directions in Biomedical Engineering, 2022
Photoplethysmography signal (PPG) provides information about the cardiovascular, respiratory, or nervous system activity. Recent studies proposed methods of apnea identification from PPG using amplitude or baseline modulation, or area under the curve. We
Rafl-Huttova Veronika, Cizek Dominik, Rafl Jakub, Rozanek Martin   +3 more
doaj   +1 more source

Fatigue notch sensitivity of steel blunt‐notched specimens

Fatigue & Fracture of Engineering Materials & Structures, 2002
ABSTRACTThe notch sensitivity of three steels with similar plain fatigue limits was analysed and modelled. The analysis was made by using a model previously derived which estimated the fatigue limit of blunt notched components by means of the parameter ktd defined as the stress concentration introduced by the notch at a distance d from the notch root ...
Chapetti, Mirco Daniel, Kitagawa, Rosa Beatriz, Miyata, T.   +2 more
openaire   +2 more sources

Notch promotes neural lineage entry by pluripotent embryonic stem cells [PDF]

, 2006
A central challenge in embryonic stem (ES) cell biology is to understand how to impose direction on primary lineage commitment. In basal culture conditions, the majority of ES cells convert asynchronously into neural cells.
Smith, Austin G, Austin G Smith, Heavey Barry, Alexandra Benchoua, Benchoua, Alexandra, Smith, Austin,, Benchoua Alexandra, Sally Lowell, Smith Austin G, Lowell, Sally; id_orcid, Smith, Austin, G., Lowell Sally, Lowell, Sally, Heavey, Barry, Barry Heavey   +14 more
core   +1 more source

Notch activates Wnt-4 signalling to control medio-lateral patterning of the pronephros [PDF]

, 2009
Previous studies have highlighted a role for the Notch signalling pathway during pronephrogenesis in the amphibian Xenopus laevis, and in nephron development in the mammalian metanephros, yet a mechanism for this function remains elusive.
Naylor, Richard, Richard W. Naylor, Naylor, RW; id_orcid, Jones, EA, Jones, Elizabeth A., Jones, E. A., Elizabeth A. Jones, Naylor, Richard William   +7 more
core   +1 more source