Results 11 to 20 of about 62,204 (160)
Frontiers in Oncology, 2021 Olaparib has been used in the treatment of triple-negative breast cancer (TNBC) with BRCA mutations. In the present study, we demonstrated the effect of miR-27-3p on the γ-secretase pathway by regulating the sensitivity of TNBC cells to olaparib.
Meng Zhao +5 more
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On the notch sensitivity of cast iron under multi-axial fatigue loading [PDF]
Fracture and Structural Integrity, 2014 This work deals with the notch sensitivity of sharp notches under multi-axial fatigue loading. The main discussion concerns the differences in notch sensitivity at high cycle fatigue regime, between tensile, torsional and combined loading.
P. Livieri, E. Maggiolini, R. Tovo
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Apnea detection from photoplethysmography signal using dicrotic notch
Current Directions in Biomedical Engineering, 2022 Photoplethysmography signal (PPG) provides information about the cardiovascular, respiratory, or nervous system activity. Recent studies proposed methods of apnea identification from PPG using amplitude or baseline modulation, or area under the curve. We
Rafl-Huttova Veronika +3 more
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Fatigue notch sensitivity of steel blunt‐notched specimens
Fatigue & Fracture of Engineering Materials & Structures, 2002 ABSTRACTThe notch sensitivity of three steels with similar plain fatigue limits was analysed and modelled. The analysis was made by using a model previously derived which estimated the fatigue limit of blunt notched components by means of the parameter ktd defined as the stress concentration introduced by the notch at a distance d from the notch root ...
Chapetti, Mirco Daniel +2 more
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Influence of microstructure on fatigue property of ultra high-strength steels
Fracture and Structural Integrity, 2019 Ultra-high-strength steels (with tensile strength higher than 980 MPa) are widely used in automobile manufacturing owing to their lightweight that contributes to fuel efficiency.
Kanji OKUDA +4 more
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Mechanical Properties and Notch Sensitivities of the Hydrogenated X70 Pipeline Steel Welded Joints [PDF]
Cailiao BaohuIn order to explore the effects of pipeline inner-wall surface defects on reliability of the hydrogen enriched compressed natural gas(HCNG) pipeline steel welded joints in long-term service， the notches in the base metal， weld seam and heat affected zone
CHEN Ye, WANG Wanli, ZHAN Xianqiang, LIU Junjian, TANG Wenming
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Molecular Metabolism, 2016 Objective: As the obesity pandemic continues to expand, novel molecular targets to reduce obesity-related insulin resistance and Type 2 Diabetes (T2D) continue to be needed.
David P. Sparling +6 more
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Notch Signaling Regulates Muscle Stem Cell Homeostasis and Regeneration in a Teleost Fish
Frontiers in Cell and Developmental Biology, 2021 Muscle regeneration is mediated by the activity of resident muscle satellite cells (muSCs) that express Pax7. In mouse Notch signaling regulates muSCs during quiescence and promotes muSC proliferation in regeneration.
Sami H. A. Sultan +3 more
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Effects of pressure sensitivity and notch geometry on notch‐tip fields [PDF]
Polymer Engineering & Science, 1998 AbstractPlane‐strain stress and slip‐line fields near the sharp and round tips of wedge‐shaped notches in perfectly plastic pressure‐sensitive materials are investigated to illustrate the effects of pressure sensitivity and notch geometry on notch‐tip fields.
Al-Abduljabbar, A., Pan, Jwo
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Endothelial Notch signaling controls insulin transport in muscle
EMBO Molecular Medicine, 2020 The role of the endothelium is not just limited to acting as an inert barrier for facilitating blood transport. Endothelial cells (ECs), through expression of a repertoire of angiocrine molecules, regulate metabolic demands in an organ‐specific manner ...
Sana S Hasan +19 more
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