Results 21 to 30 of about 1,914,304 (195)

Influence of microstructure on fatigue property of ultra high-strength steels

open access: yesFracture and Structural Integrity, 2019
Ultra-high-strength steels (with tensile strength higher than 980 MPa) are widely used in automobile manufacturing owing to their lightweight that contributes to fuel efficiency.
Kanji OKUDA   +4 more
doaj   +3 more sources

The molecular role of non-canonical Notch signaling via Deltex-1 in high grade glioma [PDF]

open access: yes, 2011
Glioblastoma Multiforme is a WHO grade IV brain tumor with glial characteristics leading to more years of life lost than any other cancer. A better understanding of GBM biology and valid animal models are the two key elements to improved therapeutic ...
Huber, Roland Martin
core   +1 more source

Mechanical Properties and Notch Sensitivities of the Hydrogenated X70 Pipeline Steel Welded Joints [PDF]

open access: yesCailiao Baohu
In order to explore the effects of pipeline inner-wall surface defects on reliability of the hydrogen enriched compressed natural gas(HCNG) pipeline steel welded joints in long-term service, the notches in the base metal, weld seam and heat affected zone
CHEN Ye, WANG Wanli, ZHAN Xianqiang, LIU Junjian, TANG Wenming
doaj   +1 more source

Adipocyte-specific blockade of gamma-secretase, but not inhibition of Notch activity, reduces adipose insulin sensitivity

open access: yesMolecular Metabolism, 2016
Objective: As the obesity pandemic continues to expand, novel molecular targets to reduce obesity-related insulin resistance and Type 2 Diabetes (T2D) continue to be needed.
David P. Sparling   +6 more
doaj   +1 more source

Notch Signaling Regulates Muscle Stem Cell Homeostasis and Regeneration in a Teleost Fish

open access: yesFrontiers in Cell and Developmental Biology, 2021
Muscle regeneration is mediated by the activity of resident muscle satellite cells (muSCs) that express Pax7. In mouse Notch signaling regulates muSCs during quiescence and promotes muSC proliferation in regeneration.
Sami H. A. Sultan   +3 more
doaj   +1 more source

The role of the notch signalling pathway in vascular smooth muscle cell apoptosis [PDF]

open access: yes, 2004
The Notch signalling system is a highly conserved method of cell-to-cell communication involved in cell fate decisions in many cell types. Until recently, the importance of the Notch signalling pathway was recognized in the embryonic but not in the adult
Sweeney, Catherine Helena
core   +2 more sources

Numb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear. [PDF]

open access: yes, 2015
The Notch signaling pathway controls differentiation of hair cells and supporting cells in the vertebrate inner ear. Here, we have investigated whether Numb, a known regulator of Notch activity in Drosophila, is involved in this process in the embryonic ...
Mark eEddison   +9 more
core   +1 more source

Endothelial Notch signaling controls insulin transport in muscle

open access: yesEMBO Molecular Medicine, 2020
The role of the endothelium is not just limited to acting as an inert barrier for facilitating blood transport. Endothelial cells (ECs), through expression of a repertoire of angiocrine molecules, regulate metabolic demands in an organ‐specific manner ...
Sana S Hasan   +19 more
doaj   +1 more source

Study on Hydrogen Embrittlement Sensitivity of L245 Seamless Steel Pipe Under 4 MPa H2 Environment [PDF]

open access: yesCailiao Baohu, 2023
In order to investigate the hydrogen embrittlement sensitivity of the low-grade pipeline steel in medium-pressure hydrogen environment,the hydrogen embrittlement sensitivity of L245 steel in air environment and 4 MPa hydrogen environment was studied by ...
DU Peien, SONG Weichen, LIU Zhi, FU Guoqiang, LI Ba, WANG Bing, LIU Qingyou
doaj   +1 more source

Notch (In)Sensitivity of Aluminum Matrix Syntactic Foams [PDF]

open access: yesMaterials, 2019
Aluminum alloy (Al99.5 or AlSi12)-based metal matrix syntactic foams (MMSFs) were produced by pressure infiltration with ~65 vol % Globocer filler (33 wt % Al2O3, 48 wt % SiO2, 19 wt % Al2O3∙SiO2). The infiltrated blocks were machined by different geometry tools in order to produce notched samples.
Attila Szlancsik   +3 more
openaire   +3 more sources

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