Results 51 to 60 of about 1,914,304 (195)

Notch Sensitivity of Glass/Polyester Laminates

open access: yesJournal of Engineering and Sustainable Development, 2008
The effect of the hole size on the fracture behavior of glass/polyester fabric laminates is experimentally studied in the flexural test. An “ANSYS” program is employed for the purpose of comparison, and for computation of the maximum stress and its ...
Muhanad Nazar Mustafa
doaj  

NOTCH pathway inactivation reprograms stem-like oral cancer cells to JAK-STAT dependent state and provides the opportunity of synthetic lethality

open access: yesTranslational Oncology, 2023
Background: We have recently provided the evidence of interconvertible cellular states, driving non-genetic heterogeneity among stem-like oral cancer cells (oral-SLCCs).
Subhashis Ghosh   +9 more
doaj   +1 more source

Inhibition of the Numb/Notch signaling pathway increases radiation sensitivity in human nasopharyngeal carcinoma cells

open access: yesKaohsiung Journal of Medical Sciences, 2019
Radiation therapy is the primary treatment for primary nasopharyngeal carcinoma (NPC). The aim of this study is to identify the effect of the Numb/Notch signaling pathway on radiation sensitivity in human NPC cells.
Er‐Dong Shen, Qiang Zeng
doaj   +1 more source

Influence of as-built surface on fatigue strength and notch sensitivity of Ti6Al4V alloy produced by DMLS

open access: yesMATEC Web of Conferences, 2018
Direct Metal Laser Sintering (DMLS) is one of the additive manufacturing technologies involving a metal powder bed and a laser source to obtain components of complex geometry.
Nicoletto Gianni   +3 more
doaj   +1 more source

Selective targeting of NOTCH-1 for therapeutic purposes in xenograft models of T-acute lymphoblastic leukemia [PDF]

open access: yes, 2013
T-cell acute lymphoblastic leukemia (T-ALL) is an heterogeneous disease, characterized by several genetic alterations and polymorphic clinical features both in children and adults.
Agnusdei, Valentina
core  

Spatiotemporal oscillations of Notch1, Dll1 and NICD are coordinated across the mouse PSM [PDF]

open access: yes, 2014
During somitogenesis, epithelial somites form from the pre-somitic mesoderm (PSM) in a periodic manner. This periodicity is regulated by a molecular oscillator, known as the 'segmentation clock', that is characterised by an oscillatory pattern of gene ...
Dale, J. Kim   +7 more
core   +1 more source

Cis-activation in the Notch signaling pathway

open access: yeseLife, 2019
The Notch signaling pathway consists of transmembrane ligands and receptors that can interact both within the same cell (cis) and across cell boundaries (trans). Previous work has shown that cis-interactions act to inhibit productive signaling.
Nagarajan Nandagopal   +2 more
doaj   +1 more source

Static notch sensitivity in orthotropic materials and composites

open access: yes, 2021
A theoretical study on defect and notch sensitivity in orthotropic materials is carried out, with the aim to make explicit the bridging between notch effect and defect sensitivity.
Zappalorto M.
core   +1 more source

On the Notch-Sensitivity and toughness of A Ceramic Composite [PDF]

open access: yesAdvanced Composites Letters, 1992
A Nicalon TM/SiC fabric (8-harness satin) reinforced alumina matrix (CMC) was loaded in tension to fracture. A coating on the surface of the fibre reduced the strength of the fibre-matrix bond, increased the toughness of the CMC by more than 3 times, and raised the unnotched strength by more than 2 times.
Keith T Kedward, Peter W R Beaumont
openaire   +1 more source

Congenital diseases caused by defective O-glycosylation of Notch receptors [PDF]

open access: yes, 2018
2018-08The Notch signaling pathway is highly conserved and essential for animal development. It is required for cell differentiation, survival, and proliferation. Regulation of Notch signaling is a crucial process for human health.
Okajima, Tetsuya, Tashima, Yuko
core   +1 more source

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