Results 211 to 220 of about 107,106 (262)
Notch Signaling Pathway Regulates Ozone-Induced Lung Circadian Rhythm Disruption. [PDF]
ToxicsZhang X, Jian X, Miao X, Jia Y.
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Significance of Notch Signaling in Salivary Gland Development and Diseases. [PDF]
J Clin MedSisto M, Lisi S.
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Glycosylation regulates Notch signalling
Nature Reviews Molecular Cell Biology, 2003Intracellular post-translational modifications such as phosphorylation and ubiquitylation have been well studied for their roles in regulating diverse signalling pathways, but we are only just beginning to understand how differential glycosylation is used to regulate intercellular signalling.
Nicola, Haines, Kenneth D, Irvine
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Science, 1995
The Notch/Lin-12/Glp-1 receptor family mediates the specification of numerous cell fates during development in Drosophila and Caenorhabditis elegans . Studies on the expression, mutant phenotypes, and developmental consequences of unregulated receptor activation have implicated these proteins
S, Artavanis-Tsakonas +2 more
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The Notch/Lin-12/Glp-1 receptor family mediates the specification of numerous cell fates during development in Drosophila and Caenorhabditis elegans . Studies on the expression, mutant phenotypes, and developmental consequences of unregulated receptor activation have implicated these proteins
S, Artavanis-Tsakonas +2 more
openaire +2 more sources
Notch signaling in reproduction
Trends in Endocrinology & Metabolism, 2021The Notch signaling pathway is conserved among mammalian species and controls proliferation, differentiation, and cell death in many organs throughout the body including the reproductive tract. Notch signaling plays critical roles in the development and function of both the male and female reproductive systems.
Genna E. Moldovan +2 more
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Science's STKE, 2006
Notch is a receptor that mediates intercellular signaling through a pathway conserved across the metazoa. It is involved in cell fate assignation and pattern formation during development. The receptor acts as a membrane-tethered transcription factor and is activated by members of the Delta, Serrate, Lag-2 family of Notch ligands, which trigger two ...
Matthias, Ehebauer +2 more
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Notch is a receptor that mediates intercellular signaling through a pathway conserved across the metazoa. It is involved in cell fate assignation and pattern formation during development. The receptor acts as a membrane-tethered transcription factor and is activated by members of the Delta, Serrate, Lag-2 family of Notch ligands, which trigger two ...
Matthias, Ehebauer +2 more
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Annual Review of Biophysics, 2021
Notch signaling is a conserved system of communication between adjacent cells, influencing numerous cell fate decisions in the development of multicellular organisms. Aberrant signaling is also implicated in many human pathologies. At its core, Notch has a mechanotransduction module that decodes receptor–ligand engagement at the cell surface under ...
David, Sprinzak, Stephen C, Blacklow
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Notch signaling is a conserved system of communication between adjacent cells, influencing numerous cell fate decisions in the development of multicellular organisms. Aberrant signaling is also implicated in many human pathologies. At its core, Notch has a mechanotransduction module that decodes receptor–ligand engagement at the cell surface under ...
David, Sprinzak, Stephen C, Blacklow
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Seminars in Cell & Developmental Biology, 1998
In addition to the core components of the Notch pathway, a number of proteins have been identified that exert positive or negative influences on Notch signaling. These include extracellular modulators, which may influence binding or activation of Notch by its ligands, cytoplasmic modulators, which presumably influence signal transduction steps after ...
V M, Panin, K D, Irvine
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In addition to the core components of the Notch pathway, a number of proteins have been identified that exert positive or negative influences on Notch signaling. These include extracellular modulators, which may influence binding or activation of Notch by its ligands, cytoplasmic modulators, which presumably influence signal transduction steps after ...
V M, Panin, K D, Irvine
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Notch signaling in neuroblastoma
Seminars in Cancer Biology, 2004Neuroblastoma is a pediatric tumor that originates from precursor cells of the sympathetic nervous system that have discontinued their normal differentiation program. This review is focused on involvement of the Notch signaling cascade in the process of differentiation in neuroblastoma cells and normal cells of the sympathetic nervous system.
Sven, Påhlman +3 more
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Notch signaling in lymphopoiesis
Seminars in Immunology, 2003Notch signaling regulates many cell fate decisions during development of multi-cellular organisms. Signals initiated by Notch influence a wide variety of processes that include lineage specification, cell survival and proliferation, and border formation.
Warren S, Pear, Freddy, Radtke
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