Results 61 to 70 of about 107,106 (262)
The Retinal Pigment Epithelium Is a Notch Signaling Niche in the Mouse Retina
Cell Reports, 2017 Summary: Notch signaling in neural progenitor cell is triggered by ligands expressed in adjacent cells. To identify the sources of active Notch ligands in the mouse retina, we negatively regulated Notch ligand activity in various neighbors of retinal ...
Taejeong Ha +8 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu +10 more
wiley +1 more source
Frontiers in Immunology, 2018 SIRT1 is reported to participate in macrophage differentiation and affect sepsis, and Notch signaling is widely reported to influence inflammation and macrophage activation.
Xiaozhi Bai +11 more
doaj +1 more source
Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials
Advanced Engineering Materials, EarlyView.Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai +2 more
wiley +1 more source
Notch and mTOR Signaling Pathways Promote Human Gastric Cancer Cell Proliferation
Neoplasia: An International Journal for Oncology Research, 2019 Notch pathway signaling is known to promote gastric stem cell proliferation, and constitutive pathway activation induces gastric tumors via mTORC1 activation in mouse genetic models.
Elise S. Hibdon +6 more
doaj +1 more source
Meta‐Rod Mechanical Metamaterials With Programmable Reconfiguration
Advanced Functional Materials, EarlyView.Existing mechanical metamaterials achieve programmable large deformations in planar square or cubic configurations, restricted by required complex boundary conditions. This research proposes a 1D metamaterial, Meta‐rod, with linear, bending, twisting, area, and volume deformation modes.
Atharva Pande, Lyes Kadem, Hang Xu
wiley +1 more source
Non-small-cell lung carcinoma: role of the Notch signaling pathway
Lung Cancer: Targets and Therapy, 2015 Levi Barse, Maurizio Bocchetta Department of Pathology, Oncology Institute, Loyola University Chicago, Maywood, IL, USA Abstract: Notch signaling plays a pivotal role during embryogenesis.
Barse L, Bocchetta M
doaj
Activation of the Notch signaling pathway promotes neurovascular repair after traumatic brain injury
Neural Regeneration Research, 2015 The Notch signaling pathway plays a key role in angiogenesis and endothelial cell formation, but it remains unclear whether it is involved in vascular repair by endothelial progenitor cells after traumatic brain injury.
Qi-shan Ran +3 more
doaj +1 more source
Advanced Functional Materials, EarlyView.MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández +7 more
wiley +1 more source
Advanced Functional Materials, EarlyView.This review evaluates strategies for electrochemical CO2 reduction to ethylene, focusing on copper‐based catalyst design and microenvironment modulation to achieve industrial‐grade performance. By leveraging operando synchrotron‐based characterizations, we provide a multiscale understanding of dynamic structural transformations and key reaction ...
Meng Zhang, Zuolong Chen, Yimin A. Wu
wiley +1 more source