Results 51 to 60 of about 75,809 (268)

Effect of Disorder and Notches on Crack Roughness [PDF]

open access: yes, 2007
We analyze the effect of disorder and notches on crack roughness in two dimensions. Our simulation results based on large system sizes and extensive statistical sampling indicate that the crack surface exhibits a universal local roughness of $\zeta_{loc}
A. Hansen   +10 more
core   +3 more sources

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Experimental and Theoretical Investigations on Mode I Crack Propagation in Notches under Cyclic Loading

open access: yesThe Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science, 2007
Research works regarding crack opening stresses covering various types of Mode I cracks initiated and growing in notches under cyclic loading are shown. A large number of parameters influence the crack opening behavior, i.e. material, crack length, notch
Alexander SAVAIDIS   +3 more
doaj  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Revisiting classical concepts of Linear Elastic Fracture Mechanics - Part III: The stress field in a double-edge notched finite strip by means of the �stress-neutralization� technique

open access: yesFracture and Structural Integrity
This is the third part of a short series of paper, revisiting some classical concepts of Linear Elastic Fracture Mechanics. Based on the solution for the single edge notched strip, discussed in Part-II, the present study deals with the stress field ...
Christos F. Markides   +1 more
doaj   +3 more sources

Notch Effect on Plastic Deformation of Metallic Glass: A Numerical Study by Revised Free-Volume Theory

open access: yesAdvances in Materials Science and Engineering, 2020
By means of a revised free-volume theory, the notch effect on metallic glass was systematically investigated by the numerical method. Simulations on specimens without notches demonstrated that the parameters being determined in this work could reasonably
J. F. Yan   +4 more
doaj   +1 more source

Proof of the Double Bubble Conjecture in R^n [PDF]

open access: yes, 2007
The least-area hypersurface enclosing and separating two given volumes in R^n is the standard double bubble.Comment: 20 pages, 22 ...
B.W. Reichardt   +12 more
core   +3 more sources

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Experimental Study of Forced- Convection from Horizontal Rectangular Fins Array into Air Duct

open access: yesAl-Khawarizmi Engineering Journal, 2019
In this work, an experimental study has been done to expect the heat characteristics and performance of the forced-convection from a heated horizontal rectangular fins array to air inside a rectangular cross-section duct.
Saad Najeeb Shehab
doaj   +1 more source

Photonic ring resonator filters for astronomical OH suppression

open access: yes, 2017
Ring resonators provide a means of filtering specific wavelengths from a waveguide, and optionally dropping the filtered wavelengths into a second waveguide. Both of these features are potentially useful for astronomical instruments.
Bland-Hawthorn, J.   +11 more
core   +1 more source

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