Results 121 to 130 of about 1,890,470 (317)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Simultaneous optimization of power factor and thermal conductivity via charge transfer effect and enhanced scattering of phonons in Si80Ge20P1/CoSi2 composites

Journal of Materiomics
SiGe based alloy is a promising medium-high temperature thermoelectric material that has been applied in the field of aerospace exploration. So far, utilizing the second phase to promote the scattering of phonons is a common way to improve the ...
Runze Shi, Jie Gao, Lei Miao, Chengyan Liu, Ying Peng, Jun-Liang Chen, Huajun Lai, Kun Hu   +7 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

An analysis of translation procedure from English into Indonesian language in novel the negotiator

, 2014
The goal of the research is to analyze the translation procedures in the novel "The Negotiator". In translation process, the translator translates the novel from source language (English) into target language (Indonesia) is to give the information and ...
Bachtiar Harsja, Fadjar, A. Malik, Zulkifli, Andi Pramono   +3 more
core  

Directivity Modeling and Simulation Analysis of a Novel Structure MEMS Piezoelectric Vector Hydrophone. [PDF]

Micromachines (Basel), 2023
Deng W, Fan Q, Li J, Wang C.
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Evolution and development of the mammalian jaw joint: Making a novel structure. [PDF]

Evol Dev, 2023
Anthwal N, Tucker AS.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A Novel Magnetic Update Operator for Quantum Evolutionary Algorithms

, 2010
Quantum Evolutionary Algorithms (QEA) are novel algorithms proposed for class of combinatorial optimization problems. The probabilistic representation of possible solutions in QEA helps the q-individuals to represent all the search space simultaneously ...
Tayarani Najaran, Mohammad, Prugel-Bennett, Adam   +1 more
core  

The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site

, 2008
Ribosome biogenesis in eukaryotes requires the participation of a large number of ribosome assembly factors. The highly conserved eukaryotic nucleolar protein Nep1 has an essential but unknown function in 18S rRNA processing and ribosome biogenesis.
Wöhnert, Jens, Hart, P. John, Meyer, Britta, Entian, Karl-Dieter, Schirf, Virgil, Kötter, Peter, Taylor, Alexander B., Demeler, Borries, Leal, Belinda Z.   +8 more
core   +1 more source