Results 71 to 80 of about 4,556,772 (353)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Transcriptomic analysis of intracellular RNA granules and small extracellular vesicles: Unmasking their overlap in a cell model of Huntington's disease

open access: yesMolecular and Cellular Probes
Huntington's disease (HD) arises from the abnormal expansion of a CAG repeat in the HTT gene. The mutant CAG repeat triggers aberrant RNA-protein interactions and translates into toxic aggregate-prone polyglutamine protein.
Deepti Kailash Nabariya   +5 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Discovering acoustic structure of novel sounds [PDF]

open access: yesThe Journal of the Acoustical Society of America, 2018
Natural sounds have substantial acoustic structure (predictability, nonrandomness) in their spectral and temporal compositions. Listeners are expected to exploit this structure to distinguish simultaneous sound sources; however, previous studies confounded acoustic structure and listening experience.
Christian E, Stilp   +2 more
openaire   +2 more sources

Electronic Structure of Novel Superconductor Ca4Al2O6Fe2As2

open access: yes, 2010
We have performed the first-principles electronic structure calculation for the novel superconductor Ca4Al2O6Fe2As2 which has the smallest a lattice parameter and the largest As height from the Fe plane among the Fe-As superconductors.
Ishibashi, Shoji   +3 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

A Novel Dual-Band “C+O” Structure Antenna

open access: yesInternational Journal of Antennas and Propagation, 2021
This article proposes a novel multiband antenna with “C + O” structure, which uses two classic circular letters and combines them. The antenna is suitable for wireless applications such as second generation (2G), third generation (3G), fourth generation (
Tangyao Xie   +5 more
doaj   +1 more source

The Architecture of a Novel Weighted Network: Knowledge Network

open access: yes, 2008
Networked structure emerged from a wide range of fields such as biological systems, World Wide Web and technological infrastructure. A deeply insight into the topological complexity of these networks has been gained.
Clark J.   +3 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Enhancing implant surfaces: mechanical stability and cytocompatibility of DNase I coatings deposited by alternating current electrophoretic deposition

open access: yesFrontiers in Bioengineering and Biotechnology
Deoxyribonuclease I (DNase I) is an enzyme that hydrolyzes the phosphodiester bonds in the DNA backbone, enabling efficient DNA degradation. This activity is particularly relevant for degrading extracellular DNA (eDNA), a key structural component of the ...
Merve Kübra Aktan   +7 more
doaj   +1 more source

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