Results 81 to 90 of about 4,556,772 (353)

The structure of a LAIR1-containing human antibody reveals a novel mechanism of antigen recognition

eLife, 2017
Antibodies are critical components of the human adaptive immune system, providing versatile scaffolds to display diverse antigen-binding surfaces. Nevertheless, most antibodies have similar architectures, with the variable immunoglobulin domains of the ...
Fu-Lien Hsieh, Matthew K Higgins
doaj   +1 more source

MAKING MEANING USING SYSTEMIC FUNCTIONAL LINGUISTICS AND VISUAL GRAMMAR ANALYSIS: COMPARISON OF SOURCE TEXT AND TARGET TEXT REFLECTED IN THE MAIN CHARACTER OF GRAPHIC NOVEL V FOR VENDETTA [PDF]

, 2017
This research presents a project designed to investigate a systemic way of analyzing metafunctions’ shifts between source texts and target texts using systemic functional linguistic (SFL) collaborated with visual grammar (VS; systemic functional ...
Nababan, Nababan, Santosa, Riyadi, Utami, Puti Yuni   +2 more
core  

Long range magnetic ordering in Na$_2$IrO$_3$

, 2011
We report a combined experimental and theoretical investigation of the magnetic structure of the honeycomb lattice magnet Na$_2$IrO$_3$, a strong candidate for a realization of a gapless spin-liquid.
Berlijn, T., Gegenwart, P., Gretarsson, H., Hill, J. P., Kim, Young-June, Ku, W., Liu, X., Singh, Yogesh, Tsvelik, A., Yin, W. -G.   +9 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Development of an Insulin‐Permeable Hydrogel Membrane Based on Photocrosslinkable Poly(2‐Alkyl‐2‐Oxazoline)s

Macromolecular Materials and Engineering
This study presents the development of insulin‐permeable hydrogel‐based composite membranes from photocrosslinkable poly(2‐alkyl‐2‐oxazoline)s. The membrane design addresses the challenge of maintaining protein structural integrity during delivery ...
Aliia Ibragimova, Daria V. Berdnikova, Maren Kipping, Swathi N. V. Raghu, Manuela S. Killian, Ulrich Jonas   +5 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Toward inorganic flexible π-shaped thermoelectric generators with high output power density: From materials to devices

Journal of Materiomics
Flexible thermoelectric generators (f-TEGs) have emerged as among the most promising candidates to address the persistent energy supply challenges associated with wearable electronics.
Kun Hu, Luohong Si, Jie Gao, Lei Miao, Sijing Zhu, Shiyuan Zhao, Jun-Liang Chen, Jianhua Zhou, Kunihito Koumoto   +8 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source