Results 61 to 70 of about 508 (167)

Nerve agents: A clear and present danger to mankind [PDF]

open access: yesScripta Medica, 2019
This editorial is written on the occasion of the 25th anniversary of the infamous sarin and VX terrorist attacks in Japan, in order to increase the awareness of the potential terrorist use of nerve agents and to urge the preparedness to cope with its ...
Stojiljković Miloš P.
doaj  

Phytotoxicity and insectoacaricidal activity of actinomycetes isolated from saline soils of arid territory

open access: yesЮг России: экология, развитие, 2020
Aim. The purpose of these studies is to assess the phytotoxicity and insectoacaricidal activity of actinomycetes culture fluid. The results of phytosanitary monitoring on plantings of crops indicate the massive development of pathogens of viral ...
L. N. Grigoryan   +4 more
doaj   +1 more source

Thermal Stability of the Guinea Green B Solution With Substrate and Its Application for the Detection of Cholinesterase Inhibitors

open access: yesAnalysis &Sensing, Volume 6, Issue 5, September 2026.
A Guinea Green B/butyrylthiocholine iodide solution offers a simple visual colorimetric approach for detecting cholinesterase inhibitors (neostigmine, VX, and A‐234). The aqueous formulation remains practically functional after 150 days at 60 °C, whereas the phosphate‐buffered variant rapidly degrades.
Lukáš Matějovský   +1 more
wiley   +1 more source

Green Computational Approach for Raman Spectroscopy Prediction: A Sustainable Method for Hazardous Chemical Database Construction

open access: yesChemistry–Methods, Volume 6, Issue 7, July 2026.
A green density functional theory‐based Raman prediction workflow is presented as a safe alternative to hazardous experimental characterization. The optimized computational model enables accurate spectral prediction, scalable database expansion, and structural differentiation using key P═O, C═N, and P–F Raman markers while minimizing waste and ...
Honghyun Kim   +3 more
wiley   +1 more source

Breathable Graphene Oxide‐Polymer Composite Membranes With Two‐Step Barrier Mechanism Against Nerve Agents

open access: yesAdvanced Functional Materials, Volume 36, Issue 37, 7 May 2026.
ABSTRACT Breathable membranes that reject chemical warfare agents (CWAs) are required for next‐generation protective apparel. A dual‐function graphene oxide (GO)‐polyamine architecture is introduced that addresses the long‐standing tradeoff between vapor transmission and CWA selectivity.
Hyungjun Kim   +6 more
wiley   +1 more source

Environment-forming activity of barley regenerants root systems in the conditions of acid soils toxicity

open access: yesАграрная наука Евро-Северо-Востока, 2018
Regenerative lines of barley 917-01, 781-04, 441-05, 530-98 obtained by cell selection on acid selective media with aluminum, were evaluated with regard to the original sorts 999-93, Novichok and standard Bios 1 in the laboratory, vegetative and field ...
O. N. Shupletsova, I. N. Shchennikova
doaj   +1 more source

From Mechanisms to Materials: Oximate Reactivity and Emerging Strategies for Organophosphate Detoxification

open access: yesChemPhysChem, Volume 27, Issue 7, 14 April 2026.
The development of effective strategies for the detoxification of organophosphorus (OP) nerve agents has evolved from the early mechanistic studies of François Terrier and collaborators, who first elucidated the exceptional nucleophilicity of α‐effect species such as oximes and hydroxamates, to the modern design of supramolecular and material‐based ...
Pedro Rodríguez‐Dafonte
wiley   +1 more source

Cholinesterases inhibited by novichok agents - in silico study of reactivation possibilities [PDF]

open access: yes, 2022
Title: Cholinesterases inhibited by novichok agents - in silico study of reacti- vation possibilities Author: Zbyněk Večeřa Department: Department of Organic and Bioorganic Chemistry Supervisor: doc. PharmDr. Jaroslav Roh, Ph.D. Advisor: PharmDr.
Večeřa, Zbyněk
core  

Acetylcholinesterase: Structure, dynamics, and interactions with organophosphorus compounds

open access: yesProtein Science, Volume 34, Issue 10, October 2025.
Abstract Acetylcholinesterase (AChE) is an enzyme that hydrolyzes the neurotransmitter acetylcholine (ACh), removing it from the synaptic cleft after the transmission of an electrical signal, making it an essential component of chemical neurotransmission. AChE is a serine hydrolase, containing a catalytic triad of Ser/His/Glu.
Li‐Wei Hung   +3 more
wiley   +1 more source

Backbone Conformation Shifts in X-ray Structures of Human Acetylcholinesterase upon Covalent Organophosphate Inhibition

open access: yesCrystals, 2021
Conformations of Cα backbones in X-ray structures of most organophosphate (OP)-inhibited human acetylcholinesterases (hAChEs) have been previously shown to be similar to that of the native hAChE.
Stephanie Luedtke   +5 more
doaj   +1 more source

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