Results 61 to 70 of about 508 (167)
Nerve agents: A clear and present danger to mankind [PDF]
This editorial is written on the occasion of the 25th anniversary of the infamous sarin and VX terrorist attacks in Japan, in order to increase the awareness of the potential terrorist use of nerve agents and to urge the preparedness to cope with its ...
Stojiljković Miloš P.
doaj
Aim. The purpose of these studies is to assess the phytotoxicity and insectoacaricidal activity of actinomycetes culture fluid. The results of phytosanitary monitoring on plantings of crops indicate the massive development of pathogens of viral ...
L. N. Grigoryan +4 more
doaj +1 more source
A Guinea Green B/butyrylthiocholine iodide solution offers a simple visual colorimetric approach for detecting cholinesterase inhibitors (neostigmine, VX, and A‐234). The aqueous formulation remains practically functional after 150 days at 60 °C, whereas the phosphate‐buffered variant rapidly degrades.
Lukáš Matějovský +1 more
wiley +1 more source
A green density functional theory‐based Raman prediction workflow is presented as a safe alternative to hazardous experimental characterization. The optimized computational model enables accurate spectral prediction, scalable database expansion, and structural differentiation using key P═O, C═N, and P–F Raman markers while minimizing waste and ...
Honghyun Kim +3 more
wiley +1 more source
ABSTRACT Breathable membranes that reject chemical warfare agents (CWAs) are required for next‐generation protective apparel. A dual‐function graphene oxide (GO)‐polyamine architecture is introduced that addresses the long‐standing tradeoff between vapor transmission and CWA selectivity.
Hyungjun Kim +6 more
wiley +1 more source
Regenerative lines of barley 917-01, 781-04, 441-05, 530-98 obtained by cell selection on acid selective media with aluminum, were evaluated with regard to the original sorts 999-93, Novichok and standard Bios 1 in the laboratory, vegetative and field ...
O. N. Shupletsova, I. N. Shchennikova
doaj +1 more source
The development of effective strategies for the detoxification of organophosphorus (OP) nerve agents has evolved from the early mechanistic studies of François Terrier and collaborators, who first elucidated the exceptional nucleophilicity of α‐effect species such as oximes and hydroxamates, to the modern design of supramolecular and material‐based ...
Pedro Rodríguez‐Dafonte
wiley +1 more source
Cholinesterases inhibited by novichok agents - in silico study of reactivation possibilities [PDF]
Title: Cholinesterases inhibited by novichok agents - in silico study of reacti- vation possibilities Author: Zbyněk Večeřa Department: Department of Organic and Bioorganic Chemistry Supervisor: doc. PharmDr. Jaroslav Roh, Ph.D. Advisor: PharmDr.
Večeřa, Zbyněk
core
Acetylcholinesterase: Structure, dynamics, and interactions with organophosphorus compounds
Abstract Acetylcholinesterase (AChE) is an enzyme that hydrolyzes the neurotransmitter acetylcholine (ACh), removing it from the synaptic cleft after the transmission of an electrical signal, making it an essential component of chemical neurotransmission. AChE is a serine hydrolase, containing a catalytic triad of Ser/His/Glu.
Li‐Wei Hung +3 more
wiley +1 more source
Conformations of Cα backbones in X-ray structures of most organophosphate (OP)-inhibited human acetylcholinesterases (hAChEs) have been previously shown to be similar to that of the native hAChE.
Stephanie Luedtke +5 more
doaj +1 more source

