Results 141 to 150 of about 23,054 (234)
Cell Death DiscoverySepsis-associated acute kidney injury (S-AKI) is characterized by complex pathological mechanisms, primarily driven by oxidative stress and inflammation, with NADPH oxidase 4 (NOX4) playing a critical role.
Jing Jia +8 more
doaj +1 more source
Journal of Experimental PharmacologyUmmul Khair Imaduddin,1 Afiat Berbudi,2,* Enny Rohmawaty3,* 1Graduate School of Master Program in Anti Aging and Aesthetic Medicine, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia; 2Parasitology Division, Department ...
Imaduddin UK, Berbudi A, Rohmawaty E
doaj
GLP-1通过NOX4信号通路拮抗AGE诱导的人脐静脉内皮细胞氧化损伤
, 2016 摘 要: 【目的】 探讨NOX4信号通路在胰高血糖素样肽-1(GLP-1)拮抗糖基化终末产物(AGE)诱导的内皮细胞氧化损伤的作用机制?【方法】 实验组分为对照组?AGE组?AGE+GLP-1组?AGE+NOX4 siRNA组及AGE+阴性siRNA组,RT-PCR检测NOX4 mRNA表达,Western Blotting技术检测NOX4蛋白表达情况,流式细胞仪检测细胞凋亡率?ROS生成水平?【结果】 与对照组相比,AGE可诱导细胞NOX4蛋白表达(P = 0.001)及NOX4 mRNA表达(P <
core
Plasma exosomal miR-25-3p alleviates acute pancreatitis-associated lung injury by inhibiting ferroptosis of type II alveolar epithelial cells <i>via</i> NOX4/NCOA4-mediated ferritinophagy. [PDF]
J Transl Int MedWang Z +11 more
europepmc +1 more source
NADPH Oxidase-Related Oxidative Stress in Parkinson's Disease-Associated Cognitive Impairment: An Evidence-Focused Review. [PDF]
Antioxidants (Basel)Choi DH, Choi IA.
europepmc +1 more source